Hypertension: genes and environment

P Hamet, Z Pausova, V Adarichev… - Journal of …, 1998 - journals.lww.com
Hypertension can be classified as either Mendelian hypertension or essential hypertension,
on the basis of the mode of inheritance. The Mendelian forms of hypertension develop as a …

Genetic variability in the renin-angiotensin system: prevalence of alleles and genotypes

JA Staessen, G Ginocchio, JG Wang… - European Journal of …, 1997 - academic.oup.com
Background Variants of the human genes coding for renin, angiotensin-converting enzyme
(ACE), angiotensinogen (AGT) and the angiotensin II type-I receptor (AT1R) are …

The deletion/insertion polymorphism of the angiotensin converting enzyme gene and cardiovascular-renal risk

JA Staessen, JG Wang, G Ginocchio… - Journal of …, 1997 - journals.lww.com
Objective This meta-analysis attempted to derive pooled estimates for the associations
between various cardiovascular-renal disorders and the deletion/insertion (D/I) …

Lack of association of the angiotensin converting enzyme gene polymorphism with essential hypertension in a Chinese population

FT Chiang, ZP Lai, TH Chern, CD Tseng, KL Hsu… - American journal of …, 1997 - Elsevier
To examine the association between insertion/deletion (I/D) polymorphism of the
angiotensin converting enzyme (ACE) gene and essential hypertension in a Chinese …

Polymorphism in the angiotensin converting enzyme but not in the angiotensinogen gene is associated with hypertension and type 2 diabetes: the Skaraborg …

K Bengtsson, M Orho-Melander, U Lindblad… - Journal of …, 1999 - journals.lww.com
Objective To study the association between polymorphisms in the angiotensin converting
enzyme (ACE) gene and angiotensinogen (AGT) gene and hypertension and/or type 2 …

Angiotensin-converting enzyme gene polymorphism in systemic hypertension

ZA Abbud, AC Wilson, NM Cosgrove… - American Journal of …, 1998 - ajconline.org
The renin angiotensin system plays an important role in the regulation of blood volume and
pressure. The angiotensin-converting enzyme (ACE) plays a key role in this system. A …

The genetics of hypertension

M Thibonnier, NJ Schork - Current opinion in genetics & development, 1995 - Elsevier
In the past few years, a number of key insights have been made concerning the genetic
basis of hypertension and blood pressure regulation. The genes responsible for two …

Renin and angiotensin‐converting enzyme genotypes in patients with essential hypertension and left ventricular hypertrophy

MJ West, KM Summers, DJ Burstow… - Clinical and …, 1994 - Wiley Online Library
The associations between left ventricular hypertrophy (LVH) and specific alleles of the renin
and angiotensin‐converting enzyme (ACE) genes were studied in patients with essential …

Genetic variants of the renin–angiotensin system and ambulatory blood pressure in essential hypertension

J Beige, O Zilch, H Hohenbleicher, J Ringel… - Journal of …, 1997 - journals.lww.com
Genetic variants of the renin–angiotensin system and ambulat... : Journal of Hypertension
Genetic variants of the renin–angiotensin system and ambulatory blood pressure in essential …

Is angiotensin I-converting enzyme a" master" disease gene?

DW Moskowitz - Diabetes Technology & Therapeutics, 2002 - liebertpub.com
Clustering of diseases has been appreciated by health insurers and epidemiologists for
some time. Co-morbidity suggests shared pathways of disease. It is by now well agreed that …