ROS production by mitochondria: function or dysfunction?

FR Palma, BN Gantner, MJ Sakiyama, C Kayzuka… - Oncogene, 2024 - nature.com
In eukaryotic cells, ATP generation is generally viewed as the primary function of
mitochondria under normoxic conditions. Reactive oxygen species (ROS), in contrast, are …

TPP-based conjugates: potential targeting ligands

S Batheja, S Gupta, KK Tejavath, U Gupta - Drug Discovery Today, 2024 - Elsevier
Highlights•In this review, the pivotal role of triphenylphosphonium (TPP) and its conjugates
have been widely explored.•The mechanistic insights of TPP-based conjugates endowing …

[PDF][PDF] The effectiveness and mechanism of action of N-acetylcysteine in cancer

DM Radomska-Leśniewska, A Figat - New trends in biomedical research … - researchgate.net
ABSTRACT Introduction: N-acetylcysteine (NAC) is a sulfhydryl substance, a derivative of
the amino acid L-cysteine, exhibiting high antioxidant properties. NAC is currently used as a …