Application of natural products in regulating ferroptosis in human diseases
L Deng, W Tian, L Luo - Phytomedicine, 2024 - Elsevier
Background Ferroptosis is a type of cell death caused by excessive iron-induced
peroxidation. It has been found to be involved in a variety of diseases, and natural products …
peroxidation. It has been found to be involved in a variety of diseases, and natural products …
Bioactive sphingolipids as emerging targets for signal transduction in cancer development
W Jia, J Yuan, J Zhang, S Li, W Lin, B Cheng - Biochimica et Biophysica …, 2024 - Elsevier
Sphingolipids, crucial components of cellular membranes, play a vital role in maintaining
cellular structure and signaling integrity. Disruptions in sphingolipid metabolism are …
cellular structure and signaling integrity. Disruptions in sphingolipid metabolism are …
[HTML][HTML] Hypoxia-induced exosomes facilitate lung pre-metastatic niche formation in hepatocellular carcinoma through the miR-4508-RFX1-IL17A-p38 MAPK-NF-κB …
W Jia, S Liang, W Lin, S Li, J Yuan, M Jin… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Background: Hypoxia plays an important role in the lung metastasis of hepatocellular
carcinoma (HCC). However, the process by which hypoxia promotes the formation of a pre …
carcinoma (HCC). However, the process by which hypoxia promotes the formation of a pre …
Novel SARS-CoV-2 inhibition properties of the anti-cancer Kang Guan Recipe herbal formula
The ongoing COVID-19 pandemic is a persistent challenge, with continued breakthrough
infections despite vaccination efforts. This has spurred interest in alternative preventive …
infections despite vaccination efforts. This has spurred interest in alternative preventive …
The role of dysregulated mRNA translation machinery in cancer pathogenesis and therapeutic value of ribosome-inactivating proteins
W Jia, J Yuan, S Li, B Cheng - … et Biophysica Acta (BBA)-Reviews on …, 2023 - Elsevier
Dysregulated protein synthesis is a hallmark of tumors. mRNA translation reprogramming
contributes to tumorigenesis, which is fueled by abnormalities in ribosome formation, tRNA …
contributes to tumorigenesis, which is fueled by abnormalities in ribosome formation, tRNA …
Oleanolic acid inhibits hypoxic tumor-derived exosomes-induced premetastatic niche formation in hepatocellular carcinoma by targeting ERK1/2-NFκB signaling
W Jia, S Liang, M Jin, S Li, J Yuan, J Zhang, W Lin… - Phytomedicine, 2024 - Elsevier
Background Pulmonary premetastatic niche (PMN) formation plays a key role in the lung
metastasis of hepatocellular carcinoma (HCC). Hypoxia promotes the secretion of tumor …
metastasis of hepatocellular carcinoma (HCC). Hypoxia promotes the secretion of tumor …
[HTML][HTML] Icaritin Exerts Anti-Cancer Effects through Modulating Pyroptosis and Immune Activities in Hepatocellular Carcinoma
Y Jiao, W Li, W Yang, M Wang, Y Xing, S Wang - Biomedicines, 2024 - mdpi.com
Icaritin (ICT), a natural compound extracted from the dried leaves of the genus Epimedium,
possesses antitumor and immunomodulatory properties. However, the mechanisms through …
possesses antitumor and immunomodulatory properties. However, the mechanisms through …