Circular RNAs (circRNAs), covalently closed noncoding RNAs, are widely expressed in
eukaryotes and viruses. They can function by regulating target gene expression, linear RNA …

Cancer stem-like cells (CSCs), a subpopulation of cancer cells, possess remarkable
capability in proliferation, self-renewal, and differentiation. Their presence is recognized as a …

Some tissue types give rise to human cancers millions of times more often than other tissue
types. Although this has been recognized for more than a century, it has never been …

Cancer stem cells (CSCs) are a subpopulation of cancer cells with stem cell properties that
sustain cancers, which may be responsible for cancer metastasis or recurrence. Lipid rafts …

Thyroid carcinoma (TC) is the most common malignancy of endocrine organs. The cell
subpopulation in the lineage hierarchy that serves as cell of origin for the different TC …

Aberrant activation of Wnt signaling is involved in the development of several epithelial
tumors. Wnt signaling includes two major types of pathways:(i) the canonical or Wnt/β …

The incidence of thyroid cancer is rapidly increasing, mostly due to the overdiagnosis and
overtreatment of differentiated thyroid cancer (TC). The increasing use of potent preclinical …

In thyrocytes, cell polarity is of crucial importance for proper thyroid function. Many intrinsic
mechanisms of self-regulation control how the key players involved in thyroid hormone (TH) …

Thyroid carcinoma is the most common endocrine malignancy, and papillary thyroid
carcinoma represents the most common thyroid cancer. Papillary thyroid carcinomas that …

Aims This study aims to explore the effect and underlying mechanism of zoledronic acid (ZA)
on the incidence of thyroid cancer (TC) tumorigenesis. Materials and methods Human …