Resolution of fibrosis in mdx dystrophic mouse after oral consumption of N-163 strain of Aureobasidium pullulans produced β-glucan

S Preethy, Y Aoki, K Minegishi, M Iwasaki… - Scientific Reports, 2023 - nature.com
Recent advances in the management of Duchenne muscular dystrophy (DMD), such as
exon skipping and gene therapy, though have reached a clinical stage, the outcome at its …

Re-examination of therapeutic management of muscular dystrophies using a vascular smooth muscle-centered approach

S Preethy, N Yamamoto, S Osaza… - Journal of Smooth …, 2023 - jstage.jst.go.jp
In contrast to the long-standing focus on the pathophysiology of skeletal muscles in the hunt
for a cure for Duchenne muscular dystrophy (DMD), we opine that the malfunctioning of …

Beneficial changes in the gut microbiome of patients with multiple sclerosis after consumption of Neu-REFIX B-glucan in a clinical trial

VD Dedeepiya, C Vetrievel, N Ikewaki, N Yamamoto… - medRxiv, 2023 - medrxiv.org
Background: Multiple sclerosis (MS) is a debilitating demyelinating disease and recent
evidences are giving cues towards correlation of disease severity to gut microbiome …

[HTML][HTML] Efficacy of N-163 beta-glucan in beneficially improving biomarkers of relevance to muscle function in patients with muscular dystrophies in a pilot clinical study

K Raghavan, T Sivakumar, K Ichiyama… - Acta …, 2023 - ncbi.nlm.nih.gov
Background Muscular dystrophies other than Duchenne muscular dystrophy (DMD) are
genetic diseases characterized by increasing muscle weakness, loss of ambulation, and …

Reduction in myocardial fibrosis in MDX mice on oral consumption of Aureobasidium Pullulans produced Neu REFIX Beta-glucans; holds potential as an adjuvant in …

S Preethy, N Yamamoto, KM Cherian, R Premsekar… - bioRxiv, 2023 - biorxiv.org
Organ fibrosis is one of the major causes of morbidity and mortality globally. Though fibrosis
in genetic diseases such as Duchenne muscular dystrophy (DMD) may be attributed to the …

[HTML][HTML] I. IDC Key-note Lecture: Trained immunity: a memory for innate host defense.

MG Netea - Journal of Stem Cells & Regenerative Medicine, 2023 - ncbi.nlm.nih.gov
The impact of gut microbiomes on health has recently become more important. More focus
should be placed on their function in neurological diseases since a number of metabolites …