[HTML][HTML] Decoding Tumor Angiogenesis for Therapeutic Advancements: Mechanistic Insights

G Kaur, B Roy - Biomedicines, 2024 - mdpi.com
Tumor angiogenesis, the formation of new blood vessels within the tumor microenvironment,
is considered a hallmark of cancer progression and represents a crucial target for …

[HTML][HTML] Examining the Pathogenesis of MAFLD and the Medicinal Properties of Natural Products from a Metabolic Perspective

Y Fu, Z Wang, H Qin - Metabolites, 2024 - mdpi.com
Metabolic-associated fatty liver disease (MAFLD), characterized primarily by hepatic
steatosis, has become the most prevalent liver disease worldwide, affecting approximately …

[HTML][HTML] Irisin: a possible marker of adipose tissue dysfunction in obesity

L Tomasello, M Pitrone, V Guarnotta… - International Journal of …, 2023 - mdpi.com
Adipose tissue (AT) secretes pro-and anti-inflammatory cytokines involved in AT
homeostasis, including tumor necrosis factor-α (TNFα) and irisin. The functionality of AT is …

[HTML][HTML] Implications of the Matrix Metalloproteinases, Their Tissue Inhibitors and Some Other Inflammatory Mediators Expression Levels in Children Obesity-Related …

A Wierzbicka-Rucińska, I Kubiszewska… - Journal of Personalized …, 2024 - mdpi.com
Objectives: Matrix metalloproteinases (MMPs) are calcium-dependent zinc-containing endo-
peptidases engaged in many biological processes including adipogenesis, angiogenesis …

[HTML][HTML] Potential Biomarkers for the Earlier Diagnosis of Kidney and Liver Damage in Acute Intermittent Porphyria

E Storjord, S Wahlin, BO Karlsen, RI Hardersen… - Life, 2023 - mdpi.com
Acute intermittent porphyria (AIP) is an inherited metabolic disorder associated with
complications including kidney failure and hepatocellular carcinoma, probably caused by …

[HTML][HTML] RNA Expression of MMP12 Is Strongly Associated with Inflammatory Bowel Disease and Is Regulated by Metabolic Pathways in RAW 264.7 Macrophages

L Arosa, M Camba-Gómez, LF Lorenzo-Martín… - International Journal of …, 2024 - mdpi.com
Macrophage metalloelastase or matrix metalloproteinase-12 (MMP12) is a macrophage-
specific proteolytic enzyme involved in the physiopathology of many inflammatory diseases …

Protective Effects and Mechanisms of Inhibiting Endoplasmic Reticulum Stress on Cold Seawater Immersion Combined with Hemorrhagic Shock

X Zhou, L Zou, H Deng, Y Zhou, Y Wu… - Journal of …, 2024 - Taylor & Francis
Purpose Cold seawater immersion aggravates hemorrhagic shock-induced homeostasis
imbalance and organ dysfunction, leading to increased mortality. Previous studies have …

[HTML][HTML] Zinc Iodide Dimethyl Sulfoxide Reduces Collagen Deposition by Increased Matrix Metalloproteinase-2 Expression and Activity in Lung Fibroblasts

M Roth, B Han, CT S'ng, BX Hoang, C Lambers - Biomedicines, 2024 - mdpi.com
Chronic inflammatory lung diseases are characterized by disease-specific extracellular
matrix accumulation resulting from an imbalance of matrix metalloproteinases (MMPs) and …

[HTML][HTML] Growth Differentiation Factor 15 and Matrix Metalloproteinase 3 in Plasma as Biomarkers for Neuropathy and Nephropathy in Type 1 Diabetes

K Billeson, E Baldimtsi, J Wahlberg… - International Journal of …, 2024 - mdpi.com
Diabetic neuropathy and nephropathy are common complications of type 1 diabetes (T1D).
The symptoms are often elusive in the early stages, and available diagnostic methods can …

Contribution of Matrix Metalloproteinase-7 Genotypes to Endometriosis Risk in Taiwan

HJ Chien, YC Wang, WS Chang, YH Hsieh… - Anticancer …, 2024 - ar.iiarjournals.org
Background/Aim: The activity and expression of matrix metalloproteinase-7 (MMP7) have
been found to be upregulated in the late stages of endometriosis. However, the contribution …