[HTML][HTML] Epigenetic changes associated with different types of stressors and suicide

G Dee, R Ryznar, C Dee - Cells, 2023 - mdpi.com
Stress is associated with various epigenetic changes. Some stress-induced epigenetic
changes are highly dynamic, whereas others are associated with lasting marks on the …

Genetics and epigenetics of self‐injurious thoughts and behaviors: Systematic review of the suicide literature and methodological considerations

S Mirza, AR Docherty, A Bakian, H Coon… - American Journal of …, 2022 - Wiley Online Library
Suicide is a multifaceted and poorly understood clinical outcome, and there is an urgent
need to advance research on its phenomenology and etiology. Epidemiological studies …

[HTML][HTML] Epigenetic marks and their relationship with BDNF in the brain of suicide victims

P Misztak, P Pańczyszyn-Trzewik, G Nowak… - PLoS …, 2020 - journals.plos.org
Background Suicide is a common phenomenon affecting people of all ages. There is a
strong relationship between suicidal ideation and depressive disorders. Increasing number …

Targeted sequencing approach: Comprehensive analysis of DNA methylation and gene expression across blood and brain regions in suicide victims

K Kouter, T Zupanc, A Videtič Paska - The World Journal of …, 2023 - Taylor & Francis
Objectives Epigenetic mechanisms are involved in regulation of many pathologies, including
suicidal behaviour. However, the factors through which epigenetics affect suicidal behaviour …

[HTML][HTML] Hippocampal neuropathology in suicide: Gaps in our knowledge and opportunities for a breakthrough

L Zhang, PJ Lucassen, E Salta, PDEM Verhaert… - Neuroscience & …, 2022 - Elsevier
Suicide is a major global hazard. There is a need for increasing suicide awareness and
effective and evidence-based interventions, targeting both suicidal ideation and conduct …

Integrative DNA methylation and gene expression analysis in the prefrontal cortex of Mexicans who died by suicide

AL Romero-Pimentel, D Almeida… - International journal …, 2021 - academic.oup.com
Background Suicide represents a major health concern, especially in developing countries.
While many demographic risk factors have been proposed, the underlying molecular …

[HTML][HTML] Molecular changes associated with suicide

D Navarro, M Marín-Mayor, A Gasparyan… - International journal of …, 2023 - mdpi.com
Suicide is a serious global public health problem, with a worrying recent increase in suicide
rates in both adolescent and adult populations. However, it is essential to recognize that …

Epigenetic studies in suicidal ideation and behavior

O Dada, J Qian, N Al-Chalabi, NJ Kolla, A Graff… - Psychiatric …, 2021 - journals.lww.com
Most psychiatric disorders are associated with an elevated risk of suicide. Suicidal behavior
is the product of the interaction of many risk factors, such as genetics and environmental …

[HTML][HTML] Gene expression analysis in postmortem brains from individuals who died by suicide: a systematic review

TB González-Castro, AD Genis-Mendoza… - Brain sciences, 2023 - mdpi.com
Around the world, more the 700,000 individuals die by suicide every year. It is necessary to
understand the mechanisms associated with suicidal behavior. Recently, an increase in …

[HTML][HTML] Epigenetic changes in the CYP2D6 gene are related to severity of suicide attempt: A cross-sectional study of suicide attempters

AED Boström, E Jamshidi, DM Manu, L Kular… - Journal of psychiatric …, 2023 - Elsevier
Background The ability to accurately estimate risk of suicide deaths on an individual level
remains elusive. Methods This study reports on a case-control study set-up from a well …