Recent advances in therapeutic targets identification and development of treatment strategies towards Pseudomonas aeruginosa infections

DRA Sanya, D Onésime, G Vizzarro, N Jacquier - BMC microbiology, 2023 - Springer
The opportunistic human pathogen Pseudomonas aeruginosa is the causal agent of a wide
variety of infections. This non-fermentative Gram-negative bacillus can colonize zones …

Sustainable production of biosurfactants via valorisation of industrial wastes as alternate feedstocks

PS Kumar, G Mohanakrishna, RV Hemavathy… - Chemosphere, 2023 - Elsevier
Globally, the rapid increase in the human population has given rise to a variety of industries,
which have produced a variety of wastes. Due to their detrimental effects on both human and …

Role of Host and Bacterial Lipids in Pseudomonas aeruginosa Respiratory Infections

P Constantino-Teles, A Jouault, L Touqui… - Frontiers in …, 2022 - frontiersin.org
The opportunistic pathogen Pseudomonas aeruginosa is one of the most common agents of
respiratory infections and has been associated with high morbidity and mortality rates. The …

Cytotoxic rhamnolipid micelles drive acute virulence in Pseudomonas aeruginosa

Q Xu, D Kang, MD Meyer, CL Pennington… - Infection and …, 2024 - Am Soc Microbiol
Pseudomonas aeruginosa is an opportunistic human pathogen that has developed multi-or
even pan-drug resistance toward most frontline and last resort antibiotics, leading to …

Geraniol attenuates virulence factors by inhibiting quorum sensing of Pseudomonas aeruginosa

WR Li, TH Zeng, ZQ Zhang, QS Shi, XB Xie - Frontiers in Microbiology, 2023 - frontiersin.org
Pseudomonas aeruginosa is a ubiquitous opportunistic pathogen that can cause severe
respiratory tract infections. Geraniol, a chemical component of essential oils, has …

The great divide: rhamnolipids mediate separation between P. aeruginosa and S. aureus

JL Bru, SJ Kasallis, R Chang, J Nguyen… - Frontiers in cellular …, 2023 - frontiersin.org
The interactions between bacterial species during infection can have significant impacts on
pathogenesis. Pseudomonas aeruginosa and Staphylococcus aureus are opportunistic …

Assessment of synergistic activity of rhamnolipid and linezolid against methicillin-resistant Staphylococcus aureus in-vitro and in-vivo with Galleria mellonella larvae …

B Kaskatepe, S Ozturk - Microbial Pathogenesis, 2023 - Elsevier
Antibiotic resistance, one of the most crucial public health problems, has increased the
interest in synergy studies of antibiotics with existing antibiotics and natural compounds to …

Chitosan-carrageenan microbeads containing nano-encapsulated curcumin: Nano-in-micro hydrogels as alternative-therapeutics for resistant pathogens associated …

SMA Ali, J Khan, R Shahid, S Shabbir… - International Journal of …, 2024 - Elsevier
Antimicrobial resistance is an issue of global relevance for the treatment of chronic wound
infections. In this study, nano-in-micro hydrogels (microbeads) of chitosan and κ …

Self-organized canals enable long-range directed material transport in bacterial communities

Y Li, S Liu, Y Zhang, ZJ Seng, H Xu, L Yang, Y Wu - Elife, 2022 - elifesciences.org
Long-range material transport is essential to maintain the physiological functions of
multicellular organisms such as animals and plants. By contrast, material transport in …

Enhanced low-cost optimization strategies for antimicrobial rhamnolipid production by Pseudomonas aeruginosa PAO1

MMA Elsoud, MM Elhateir, SF Hasan… - Bioresource Technology …, 2024 - Elsevier
The use of advanced biotechnological methods with agro-industrial waste is an outstanding
approach for low-cost production. This study aimed to enhance rhamnolipid production by …