Sleep and cardiovascular risk

L Korostovtseva, M Bochkarev… - Sleep Medicine …, 2021 - sleep.theclinics.com
The recent guidelines for cardiovascular prevention released by the American College of
Cardiology/American Heart Association (2019) state that counseling on sleep and sleep …

Antivascular endothelial growth factor‐A therapy: a novel personalized treatment approach for psoriasis

A Luengas‐Martinez, R Paus… - British Journal of …, 2022 - academic.oup.com
Chronic plaque psoriasis is an inflammatory skin disease in which genetic predisposition
along with environmental factors lead to the development of the disease, which affects 2% of …

Circadian rhythms in psoriasis and the potential of chronotherapy in psoriasis management

A Luengas‐Martinez, R Paus, M Iqbal… - Experimental …, 2022 - Wiley Online Library
The physiology and pathology of the skin are influenced by daily oscillations driven by a
master clock located in the brain, and peripheral clocks in individual cells. The pathogenesis …

Is obstructive sleep apnea a circadian rhythm disorder?

J Šmon, E Kočar, T Pintar… - Journal of sleep …, 2023 - Wiley Online Library
Obstructive sleep apnea is the most common sleep‐related breathing disorder worldwide
and remains underdiagnosed. Its multiple associated comorbidities contribute to a …

The circadian protein BMAL1 supports endothelial cell cycle during angiogenesis

M Astone, RE Oberkersch, G Tosi… - Cardiovascular …, 2023 - academic.oup.com
Aims The circadian clock is an internal biological timer that co-ordinates physiology and
gene expression with the 24-h solar day. Circadian clock perturbations have been …

Stroke in the time of circadian medicine

P Mergenthaler, JS Balami, AA Neuhaus… - Circulation …, 2024 - Am Heart Assoc
Time-of-day significantly influences the severity and incidence of stroke. Evidence has
emerged not only for circadian governance over stroke risk factors, but also for important …

Circadian rhythms of risk factors and management in atherosclerotic and hypertensive vascular disease: Modern chronobiological perspectives of an ancient disease

YJ Geng, MH Smolensky, O Sum-Ping… - Chronobiology …, 2023 - Taylor & Francis
Atherosclerosis, a chronic inflammatory disease of the arteries that appears to have been as
prevalent in ancient as in modern civilizations, is predisposing to life-threatening and life …

An overview of the circadian clock in the frame of chronotherapy: from bench to bedside

A Vandenberghe, M Lefranc, A Furlan - Pharmaceutics, 2022 - mdpi.com
Most living organisms in both the plant and animal kingdoms have evolved processes to
stay in tune with the alternation of day and night, and to optimize their physiology as a …

Systematic review and quality evaluation of published human ingestion-time trials of blood pressure-lowering medications and their combinations

RC Hermida, RG Hermida-Ayala, A Mojon… - Chronobiology …, 2021 - Taylor & Francis
ABSTRACT The pharmacokinetics (PK)–absorption, distribution, metabolism, and
elimination–and pharmacodynamics (PD) of hypertension medications can be significantly …

Dopamine D1 receptor-mediated regulation of Per1, Per2, CLOCK, and BMAL1 expression in the suprachiasmatic nucleus in adult male rats

S Mesgar, SB Jameie, A Aliaghaei, S Parvardeh… - Journal of Molecular …, 2022 - Springer
Photic and non-photic inputs are reported to affect clock gene expressions and behavioral
activities in the SCN. However, it is not known whether dopaminergic input mediates these …