The glucocorticoid receptor gene (NR3C1) is linked to and associated with polycystic ovarian syndrome in Italian families

S Syed, C Gragnoli - Journal of ovarian research, 2024 - Springer
Objectives Components of the hypothalamic-pituitary axis (HPA) pathway are potential
mediators of the genetic risk of polycystic ovarian syndrome (PCOS). Impaired glucocorticoid …

Impose of KNDy/GnRH neural circuit in PCOS, ageing, cancer and Alzheimer's disease: StAR actions in prevention of neuroendocrine dysfunction

SP Panda, A Kesharwani, GD Singh, D Prasanth… - Ageing Research …, 2023 - Elsevier
Abstract The Kisspeptin1 (KISS1)/neurokinin B (NKB)/Dynorphin (Dyn)[KNDy] neurons in the
hypothalamus regulate the reproduction stage in human beings and rodents. KNDy neurons …

[PDF][PDF] Novel linkage and association of TCF7L2 variants with PCOS in Italian families.

M Amin, L del Bosque-Plata… - European Review for …, 2023 - europeanreview.org
OBJECTIVE: Transcription factor 7-like 2 (TCF7L2) gene variants confer risk for type 2
diabetes and metabolic traits. We investigated the role of TCF7L2-variants in polycystic …

Circulating microparticles as indicators of cardiometabolic risk in PCOS

B Yalameha, HR Nejabati, M Nouri - Clinica Chimica Acta, 2022 - Elsevier
Polycystic ovary syndrome (PCOS), the most prevalent endocrine disturbance of the female
reproductive system, is associated with several pathologic conditions, such as metabolic …

Polycystic Ovary Syndrome and Irritable Bowel Syndrome: Is There a Common Pathway?

M Saei Ghare Naz, V Ghasemi… - Endocrinology …, 2024 - Wiley Online Library
Objective Little is known about how polycystic ovary syndrome (PCOS) is linked to irritable
bowel syndrome (IBS). This study aimed to review the existing literature regarding the …

Possible Association of Three Polymorphisms in Cytokine TNF-alpha (238G/A, 308G/A, 1031T/C) with Polycystic Ovary Syndrome: A Systematic Review and Meta …

P Gowtham, K Harini, A Thirumalai, P Pallavi… - … Research and Therapy, 2023 - bmrat.com
Background: Polycystic ovarian syndrome (PCOS) cases have recently increased drastically
among women during ovulation. The etiology of this endocrine disorder remains complex …

[HTML][HTML] Women with polycystic ovary syndrome: A review of susceptibility to type 2 diabetes

SY Layacha, DA Biswas - Cureus, 2023 - ncbi.nlm.nih.gov
The polycystic ovarian syndrome affects many women today. Previous research has
demonstrated a direct link between it and serious ailments such as type 2 diabetes, heart …

The role of glycated hemoglobin in the diagnosis of prediabetes and diabetes mellitus in young women with polycystic ovary syndrome

RH Melo, AG Pontes, LRMG Delmanto… - Clinical …, 2024 - Wiley Online Library
Objective To compare glycated hemoglobin (HbA1c) and the oral glucose tolerance test
(OGTT) for the diagnosis of prediabetes and diabetes in young women with polycystic ovary …

Association of free testosterone, glucose level and obesity among women with polycystic ovary syndrome in Soran city, Kurdistan-Iraq

PJ Jalil, BH Shnawa, MH Ahmed - Clínica e Investigación en Ginecología y …, 2023 - Elsevier
Background Polycystic ovary syndrome (PCOS) is the most common endocrinopathy
affecting approximately 5–10% of women of reproductive age and it is also a major cause of …

[HTML][HTML] Linkage and association of rs3110045 and rs28499085 variants in the thyrotropin-releasing hormone receptor (TRHR) gene with the risk of familial type 2 …

R Wu, C Gragnoli - Aspects of Molecular Medicine, 2024 - Elsevier
Abstract Type 2 diabetes (T2D) is a chronic and prevalent multisystemic disease that
significantly increases morbidity and mortality. Dysfunction of the thyroid hormone system is …