N-Acetyl-Aspartyl-Glutamate in Brain Health and Disease
C Morland, K Nordengen - International Journal of Molecular Sciences, 2022 - mdpi.com
N-acetyl-aspartyl-glutamate (NAAG) is the most abundant dipeptide in the brain, where it
acts as a neuromodulator of glutamatergic synapses by activating presynaptic metabotropic …
acts as a neuromodulator of glutamatergic synapses by activating presynaptic metabotropic …
Potential brain recovery of frontostriatal circuits in heroin users after prolonged abstinence: A preliminary study
L Lu, W Yang, X Zhang, F Tang, Y Du, L Fan… - Journal of Psychiatric …, 2022 - Elsevier
Neuroscientists have devoted efforts to explore potential brain recovery after prolonged
abstinence in heroin users (HU). However, not much is known about whether frontostriatal …
abstinence in heroin users (HU). However, not much is known about whether frontostriatal …
[HTML][HTML] Dynamics and correlations in multiplex immune profiling reveal persistent immune inflammation in male drug users after withdrawal
GF Re, J Jia, Y Xu, Z Zhang, ZR Xie, D Kong… - International …, 2022 - Elsevier
Drug withdrawal elicits immune responses that contribute to the development of withdrawal
symptoms and relapse. The understanding of the immunologic dynamics after drug …
symptoms and relapse. The understanding of the immunologic dynamics after drug …
Exploring spatial cognitive process among STEM students and its role in STEM education: A cognitive neuroscience perspective
X Li, W Wang - Science & Education, 2021 - Springer
Spatial ability is a powerful systematic source of individual differences in the areas of
science, technology, engineering, and technology (STEM). Abundant research has …
science, technology, engineering, and technology (STEM). Abundant research has …
[HTML][HTML] Ketamine metabolite alleviates morphine withdrawal-induced anxiety via modulating nucleus accumbens parvalbumin neurons in male mice
Y Chen, P Yan, S Wei, Y Zhu, J Lai, Q Zhou - Neurobiology of Disease, 2023 - Elsevier
Opioid withdrawal generates extremely unpleasant physical symptoms and negative
affective states. A rapid relief of opioid withdrawal-induced anxiety has obvious clinical …
affective states. A rapid relief of opioid withdrawal-induced anxiety has obvious clinical …
Role of GABRD gene methylation in the nucleus accumbens in heroin-seeking behavior in rats
Q Hong, W Xu, Z Lin, J Liu, W Chen, H Zhu… - Frontiers in …, 2021 - frontiersin.org
Epigenetic modifications such as DNA methylation play important roles in regulating gene
expression and may mediate neuroplasticity and lead to drug-induced aberrant behaviors …
expression and may mediate neuroplasticity and lead to drug-induced aberrant behaviors …
Buprenorphine reduces methamphetamine intake and drug seeking behavior via activating nociceptin/orphanin FQ peptide receptor in rats
F Wang, W Shen, Y Cai, X Zhang, H Du, M Lai… - Frontiers in …, 2022 - frontiersin.org
Buprenorphine, which has been approved for the treatment of opioid dependence, reduces
cocaine consumption by co-activating μ-opioid receptors and nociceptin/orphanin FQ …
cocaine consumption by co-activating μ-opioid receptors and nociceptin/orphanin FQ …
A comparison of reinforcing effectiveness and drug-seeking reinstatement of 2-fluorodeschloroketamine and ketamine in self-administered rats
H Du, M Lai, D Zhuang, D Fu, Y Zhou… - Frontiers in Molecular …, 2022 - frontiersin.org
2-Fluorodeschloroketamine (2F-DCK), a structural analog of ketamine, has been reported to
cause impaired consciousness, agitation, and hallucination in abuse cases. It has similar …
cause impaired consciousness, agitation, and hallucination in abuse cases. It has similar …
Clinical and cognitive effects of computer assisted cognitive remediation method in Turkish men with opioid use disorder: a randomized controlled trial
N Taştekin, B Ünübol, M Yazıcı - Substance Use & Misuse, 2022 - Taylor & Francis
Objective: Substance use disorders are associated with significant cognitive impairments
causing many individual or social problems besides poor treatment outcomes. The cognitive …
causing many individual or social problems besides poor treatment outcomes. The cognitive …
Cognitive impairments in patients with GHB use disorder predict relapse in GHB use
H Beurmanjer, CJWH Bruijnen, PGJ Greeven… - European Addiction …, 2022 - karger.com
Background: The recreational use of gamma hydroxybutyrate (GHB) is associated with
frequent overdoses, coma and the risk of developing GHB use disorder (GUD). Several …
frequent overdoses, coma and the risk of developing GHB use disorder (GUD). Several …