Exploring parkinson-associated kinases for CRISPR/cas9-based gene editing: beyond alpha-synuclein
HM Mansour, AS El-Khatib - Ageing Research Reviews, 2023 - Elsevier
Parkinson's disease (PD) is a debilitating neurodegenerative disorder characterized by the
loss of dopaminergic neurons in the substania nigra (SN) and is associated with progressive …
loss of dopaminergic neurons in the substania nigra (SN) and is associated with progressive …
The SH-SY5Y cell line: a valuable tool for Parkinson's disease drug discovery
Introduction Owing to limited efficient treatment strategies for highly prevalent and
distressing Parkinson's disease (PD), an impending need emerged for deciphering new …
distressing Parkinson's disease (PD), an impending need emerged for deciphering new …
High yield of functional dopamine-like neurons obtained in NeuroForsk 2.0 medium to study acute and chronic rotenone effects on oxidative stress, autophagy, and …
DA Quintero-Espinosa, C Velez-Pardo… - International Journal of …, 2023 - mdpi.com
Several efforts to develop new protocols to differentiate in in vitro human mesenchymal
stromal cells (hMSCs) into dopamine (DA) neurons have been reported. We have …
stromal cells (hMSCs) into dopamine (DA) neurons have been reported. We have …
[HTML][HTML] LRRK2 kinase inhibition protects against Parkinson's disease-associated environmental toxicants
NM Ilieva, EK Hoffman, MA Ghalib… - Neurobiology of …, 2024 - Elsevier
Idiopathic Parkinson's disease (PD) is epidemiologically linked with exposure to toxicants
such as pesticides and solvents, which comprise a wide array of chemicals that pollute our …
such as pesticides and solvents, which comprise a wide array of chemicals that pollute our …
Rotenone Induces a Neuropathological Phenotype in Cholinergic-like Neurons Resembling Parkinson's Disease Dementia (PDD)
D Giraldo-Berrio, M Mendivil-Perez… - Neurotoxicity …, 2024 - Springer
Parkinson's disease with dementia (PDD) is a neurological disorder that clinically and
neuropathologically overlaps with Parkinson's disease (PD) and Alzheimer's disease (AD) …
neuropathologically overlaps with Parkinson's disease (PD) and Alzheimer's disease (AD) …
Neuroprotective Effects of the Nutraceutical Dehydrozingerone and Its C2-Symmetric Dimer in a Drosophila Model of Parkinson's Disease
MD Setzu, I Mocci, D Fabbri, P Carta, P Muroni… - Biomolecules, 2024 - mdpi.com
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the loss of
dopaminergic neurons responsible for unintended or uncontrollable movements. Mutations …
dopaminergic neurons responsible for unintended or uncontrollable movements. Mutations …
The severity assessment of Parkinson's disease based on plasma inflammatory factors and third ventricle width by transcranial sonography
Y Lu, W Dong, X Xue, J Sun, J Yan… - CNS Neuroscience …, 2024 - Wiley Online Library
Abstract Background Predicting Parkinson's disease (PD) can provide patients with targeted
therapies. However, disease severity can be roughly evaluated in clinical practice based on …
therapies. However, disease severity can be roughly evaluated in clinical practice based on …
Research on the signaling pathways related to the intervention of traditional Chinese medicine in Parkinson's disease: A literature review
X Jin, W Dong, K Chang, Y Yan - Journal of Ethnopharmacology, 2024 - Elsevier
Ethnopharmacological relevance Parkinson's disease (PD) is the most common progressive
neurodegenerative disorder affecting more than 10 million people worldwide and is …
neurodegenerative disorder affecting more than 10 million people worldwide and is …