Heart disease and stroke statistics—2022 update: a report from the American Heart Association

CW Tsao, AW Aday, ZI Almarzooq, A Alonso… - Circulation, 2022 - Am Heart Assoc
Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

Heart disease and stroke statistics—2023 update: a report from the American Heart Association

CW Tsao, AW Aday, ZI Almarzooq, CAM Anderson… - Circulation, 2023 - Am Heart Assoc
Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

2024 heart disease and stroke statistics: a report of US and global data from the American Heart Association

SS Martin, AW Aday, ZI Almarzooq, CAM Anderson… - Circulation, 2024 - Am Heart Assoc
BACKGROUND: The American Heart Association (AHA), in conjunction with the National
Institutes of Health, annually reports the most up-to-date statistics related to heart disease …

[HTML][HTML] Alzheimer's disease: an update and insights into pathophysiology

MB Abubakar, KO Sanusi, A Ugusman… - Frontiers in aging …, 2022 - frontiersin.org
Alzheimer's disease (AD) is an irreversible brain disorder associated with slow, progressive
loss of brain functions mostly in older people. The disease processes start years before the …

The role of brain vasculature in neurodegenerative disorders

MD Sweeney, K Kisler, A Montagne, AW Toga… - Nature …, 2018 - nature.com
Adequate supply of blood and structural and functional integrity of blood vessels are key to
normal brain functioning. On the other hand, cerebral blood flow shortfalls and blood–brain …

Vascular dysfunction—the disregarded partner of Alzheimer's disease

MD Sweeney, A Montagne, AP Sagare, DA Nation… - Alzheimer's & …, 2019 - Elsevier
Increasing evidence recognizes Alzheimer's disease (AD) as a multifactorial and
heterogeneous disease with multiple contributors to its pathophysiology, including vascular …

Post-stroke cognitive impairment: epidemiology, risk factors, and management

YY Huang, SD Chen, XY Leng, K Kuo… - Journal of …, 2022 - content.iospress.com
Stroke, characterized as a neurological deficit of cerebrovascular cause, is very common in
older adults. Increasing evidence suggests stroke contributes to the risk and severity of …

Association of factors with elevated amyloid burden in clinically normal older individuals

RA Sperling, MC Donohue, R Raman, CK Sun… - JAMA …, 2020 - jamanetwork.com
Importance The Anti-Amyloid Treatment in Asymptomatic Alzheimer disease (A4) Study is an
ongoing prevention trial in clinically normal older individuals with evidence of elevated brain …

[HTML][HTML] Fibrinogen induces microglia-mediated spine elimination and cognitive impairment in an Alzheimer's disease model

M Merlini, VA Rafalski, PER Coronado, TM Gill… - Neuron, 2019 - cell.com
Cerebrovascular alterations are a key feature of Alzheimer's disease (AD) pathogenesis.
However, whether vascular damage contributes to synaptic dysfunction and how it …

Preventing dementia by preventing stroke: the Berlin Manifesto

V Hachinski, K Einhäupl, D Ganten, S Alladi… - Alzheimer's & …, 2019 - Elsevier
The incidence of stroke and dementia are diverging across the world, rising for those in low-
and middle-income countries and falling in those in high-income countries. This suggests …