This review addresses the oncopharmacological properties of curcumin at the molecular
level. First, the interactions between curcumin and its molecular targets are addressed on …

Prostanoids are cyclic, oxygenated products ofω3 andω6 20-and 22-carbon essential fatty
acids (FAs) that are formed enzymatically through “cyclooxygenases”. Prostaglandin …

Objective This study is to investigate the role of gut dysbiosis in triggering inflammation in
the brain and its contribution to Alzheimer's disease (AD) pathogenesis. Design We …

Prostaglandin E2 (PGE2) is a principal mediator of inflammation in diseases such as
rheumatoid arthritis and osteoarthritis. Nonsteroidal anti-inflammatory medications (NSAIDs) …

A single gene encodes the key enzyme for estrogen biosynthesis termed aromatase,
inhibition of which effectively eliminates estrogen production. Aromatase inhibitors …

Prostaglandin E2 (PGE2) is the most abundant prostaglandin in the human body. It has a
large number of biological actions that it exerts via four types of receptors, EP1–4. PGE2 is …

Dietary fish oil containing ω3 highly unsaturated fatty acids has cardioprotective and anti-
inflammatory effects. Prostaglandins (PGs) and thromboxanes are produced in vivo both …

Selective inhibitors of cyclooxygenase (COX)-2 afford relief from pain and inflammation.
They could also prove useful in the chemoprevention of cancer and are being investigated …

Cyclooxygenases (COXs) oxidize arachidonic acid to prostaglandin (PG) G 2 and H 2
followed by PG synthases that generates PGs and thromboxane (TX) A 2. COXs are divided …

Long regarded as proinflammatory molecules, prostaglandins (PGs) also have anti-
inflammatory effects. Both prostaglandin D2 (PGD2) and its dehydration end product 15 …