[HTML][HTML] The role of resveratrol in cancer therapy

JH Ko, G Sethi, JY Um, MK Shanmugam… - International journal of …, 2017 - mdpi.com
Natural product compounds have recently attracted significant attention from the scientific
community for their potent effects against inflammation-driven diseases, including cancer. A …

Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications

BN Singh, S Shankar, RK Srivastava - Biochemical pharmacology, 2011 - Elsevier
An expanding body of preclinical evidence suggests EGCG, the major catechin found in
green tea (Camellia sinensis), has the potential to impact a variety of human diseases …

Foxo3 activity promoted by non-coding effects of circular RNA and Foxo3 pseudogene in the inhibition of tumor growth and angiogenesis

W Yang, WW Du, X Li, AJ Yee, BB Yang - Oncogene, 2016 - nature.com
It has recently been shown that the upregulation of a pseudogene specific to a protein-
coding gene could function as a sponge to bind multiple potential targeting microRNAs …

Resveratrol and clinical trials: the crossroad from in vitro studies to human evidence

J Tomé-Carneiro, M Larrosa… - Current …, 2013 - ingentaconnect.com
Resveratrol (3, 5, 4'-trihydroxy-trans-stilbene) is a non-flavonoid polyphenol that may be
present in a limited number of foodstuffs such as grapes and red wine. Resveratrol has been …

FOXO transcription factors in cancer development and therapy

A Coomans de Brachène, JB Demoulin - Cellular and molecular life …, 2016 - Springer
The forkhead box O (FOXO) transcription factors are considered as tumor suppressors that
limit cell proliferation and induce apoptosis. FOXO gene alterations have been described in …

Targeting of cancer cell death mechanisms by resveratrol: a review

X Fu, M Li, C Tang, Z Huang, M Najafi - Apoptosis, 2021 - Springer
Cancer cell death is the utmost aim in cancer therapy. Anti-cancer agents can induce
apoptosis, mitotic catastrophe, senescence, or autophagy through the production of free …

[HTML][HTML] Mechanism of resveratrol-induced programmed cell death and new drug discovery against cancer: a review

JY Jang, E Im, ND Kim - International journal of molecular sciences, 2022 - mdpi.com
Resveratrol (3, 5, 4′-trihydroxy-trans-stilbene), a polyphenol found in grapes, red wine,
peanuts, and apples, has been reported to exhibit a wide range of biological and …

FOXO3a in cancer drug resistance

Y Liu, Y Wang, X Li, Y Jia, J Wang, X Ao - Cancer Letters, 2022 - Elsevier
Cancer is one of the major causes of death and a significant obstacle to increasing life
expectancy worldwide. Chemotherapy remains the first-line adjuvant therapeutic option for …

[HTML][HTML] Resveratrol inhibits breast cancer stem-like cells and induces autophagy via suppressing Wnt/β-catenin signaling pathway

Y Fu, H Chang, X Peng, Q Bai, L Yi, Y Zhou, J Zhu… - PloS one, 2014 - journals.plos.org
Resveratrol, a natural polyphenolic compound, is abundantly found in plant foods and has
been extensively studied for its anti-cancer properties. Given the important role of CSCs …

[HTML][HTML] Re-evaluating the role of FOXOs in cancer

M Hornsveld, TB Dansen, PW Derksen… - Seminars in cancer …, 2018 - Elsevier
FOXO transcription factors are negatively regulated by the PI3K-PKB/AKT signaling pathway
and have been mainly considered to be tumor suppressors due to their inhibitory effect on …