TRP channels in inflammatory bowel disease: Potential therapeutic targets
Y Du, J Chen, L Shen, B Wang - Biochemical Pharmacology, 2022 - Elsevier
Given the high rate of nonresponse or resistance to current inflammatory bowel disease
(IBD) treatments, novel drug targets and biomarkers that aid in therapeutic prediction are …
(IBD) treatments, novel drug targets and biomarkers that aid in therapeutic prediction are …
Transient receptor potential vanilloid 1 inhibition reduces brain damage by suppressing neuronal apoptosis after intracerebral hemorrhage
CC Chen, CH Ke, CH Wu, HF Lee, Y Chao… - Brain …, 2024 - Wiley Online Library
Intracerebral hemorrhage (ICH) induces a complex sequence of apoptotic cascades and
inflammatory responses, leading to neurological impairment. Transient receptor potential …
inflammatory responses, leading to neurological impairment. Transient receptor potential …
Molecular mechanisms of MrgprA3‐independent activation of the transient receptor potential ion channels TRPA1 and TRPV1 by chloroquine
TC Fricke, S Pantke, B Lüttmann… - British Journal of …, 2023 - Wiley Online Library
Background and Purpose Itch is associated with several pathologies and is a common drug‐
induced side effect. Chloroquine (CQ) is reported to induce itch by activating the Mas …
induced side effect. Chloroquine (CQ) is reported to induce itch by activating the Mas …
[HTML][HTML] Sickle cell disease patient plasma sensitizes iPSC-derived sensory neurons from sickle cell disease patients
RL Allison, A Burand, DN Torres, AM Brandow… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Individuals living with sickle cell disease (SCD) experience severe recurrent acute and
chronic pain. In order to develop novel therapies, it is necessary to better understand the …
chronic pain. In order to develop novel therapies, it is necessary to better understand the …