Glutamate is the predominant excitatory neurotransmitter in the central nervous system.
Excitatory amino acid transporter 2 (EAAT2) is primarily responsible for clearance of …

The basic mechanism of the major neurodegenerative diseases, including neurogenic pain,
needs to be agreed upon before rational treatments can be determined, but this knowledge …

Ceftriaxone is a beta-lactam antibiotic that increases the expression of the major glutamate
transporter, GLT-1. As such, ceftriaxone ameliorates symptoms across multiple rodent …

To date, there is no cure or disease-modifying agents available for most well-known
neurological disorders. Current therapy is typically focused on relieving symptoms and …

One of the major players in the pathophysiology of cerebral ischemia is disrupted
homeostasis of glutamatergic neurotransmission, resulting in elevated extracellular …

Ceftriaxone (Cef) selectively increases the expression of glial glutamate transporter‐1 (GLT‐
1), which was thought to be neuroprotective in some circumstances. However, the effect of …

Glutamate is the predominant excitatory neurotransmitter in the mammalian CNS. It
mediates essentially all rapid excitatory signaling. Dysfunction of glutamatergic signaling …

The present study is designed to investigate the role of glutamate transporter in
neuroprotection of ceftriaxone against MPTP induced PD animal model. Young male Wistar …

Neuron‐secreted factors induce astrocytic expression of the glutamate transporter, GLT‐1
(excitatory amino acid transporter 2). In addition to their elaborate anatomic relationships …

Parkinson's disease is a neurodegenerative disorder characterized by the loss of dopamine
neurons in the substantia nigra pars compacta along with decreased striatal dopamine …