Background Prurigo nodularis is a chronic, debilitating, and severely pruritic
neuroimmunologic skin disease. Nemolizumab, an interleukin-31 receptor alpha antagonist …

Chronic prurigo (CPG) is a neuroinflammatory, fibrotic dermatosis that is defined by the
presence of chronic pruritus (itch lasting longer than 6 weeks), scratch-associated …

Pruritus (or itch) is an unpleasant sensation leading to a desire to scratch. In the epidermis,
there are selective C or Aδ epidermal nerve endings that are pruriceptors. At their other …

Background Prurigo nodularis is a chronic skin disease characterised by intensely pruritic,
hyperkeratotic nodules. Vixarelimab, a human monoclonal antibody, binds to the beta …

Pruritus is the most common symptom of dermatological disorders, and prurigo nodularis
(PN) is notorious for intractable and severe itching. Conventional treatments often yield …

Background Prurigo nodularis (PN) presents with intensely itchy hard nodules. Despite
being limited to the skin, PN was noted to be associated with systemic diseases including …

Abstract (a) Number of ambulatory visits (n= 441), inpatient stays (n= 339) and inpatient stay
days (n= 166) per patient due to chronic prurigo in per cent and absolute numbers. y-axis …

Background Prurigo nodularis (PN) is a neuroimmunological skin disease. Severe itching is
the most challenging symptom which affects patients' quality of life. T helper 2-derived …

Prurigo is a reactive, hyperplastic skin condition characterized by pruritic papules, plaques,
and/or nodules. The temporal classification includes acute/subacute and chronic disease (≥ …

Chronic pruritus that lasts for over 6 weeks can present in various forms, like papules,
nodules, and plaque types, with prurigo nodularis (PN) being the most prevalent. The …