[HTML][HTML] Complex interplay between autophagy and oxidative stress in the development of pulmonary disease

W Ornatowski, Q Lu, M Yegambaram, AE Garcia… - Redox biology, 2020 - Elsevier
The autophagic pathway involves the encapsulation of substrates in double-membraned
vesicles, which are subsequently delivered to the lysosome for enzymatic degradation and …

Cellular signalling pathways mediating the pathogenesis of chronic inflammatory respiratory diseases: an update

M Mehta, DS Dhanjal, KR Paudel, B Singh… - …, 2020 - Springer
Respiratory disorders, especially non-communicable, chronic inflammatory diseases, are
amongst the leading causes of mortality and morbidity worldwide. Respiratory diseases …

Redox signaling at the crossroads of human health and disease

J Zuo, Z Zhang, M Luo, L Zhou, EC Nice, W Zhang… - MedComm, 2022 - Wiley Online Library
Redox biology is at the core of life sciences, accompanied by the close correlation of redox
processes with biological activities. Redox homeostasis is a prerequisite for human health …

Chronic obstructive pulmonary disease and atherosclerosis: common mechanisms and novel therapeutics

K Brassington, S Selemidis, S Bozinovski… - Clinical …, 2022 - portlandpress.com
Chronic obstructive pulmonary disease (COPD) and atherosclerosis are chronic irreversible
diseases, that share a number of common causative factors including cigarette smoking …

COPD and stroke: are systemic inflammation and oxidative stress the missing links?

V Austin, PJ Crack, S Bozinovski, AA Miller… - Clinical …, 2016 - portlandpress.com
Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow
limitation and loss of lung function, and is currently the third largest cause of death in the …

Mechanisms, pathophysiology and currently proposed treatments of chronic obstructive pulmonary disease

SO Rodrigues, CMC Cunha, GMV Soares, PL Silva… - Pharmaceuticals, 2021 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is one of the leading global causes of
morbidity and mortality. A hallmark of COPD is progressive airflow obstruction primarily …

[HTML][HTML] Pathobiological mechanisms underlying metabolic syndrome (MetS) in chronic obstructive pulmonary disease (COPD): clinical significance and therapeutic …

SMH Chan, S Selemidis, S Bozinovski… - Pharmacology & …, 2019 - Elsevier
Chronic obstructive pulmonary disease (COPD) is a major incurable global health burden
and is currently the 4th largest cause of death in the world. Importantly, much of the disease …

[HTML][HTML] Phosphodiesterases as therapeutic targets for respiratory diseases

H Zuo, I Cattani-Cavalieri, N Musheshe… - Pharmacology & …, 2019 - Elsevier
Chronic respiratory diseases, such as chronic obstructive pulmonary disease (COPD) and
asthma, affect millions of people all over the world. Cyclic adenosine monophosphate …

The impact of tobacco cigarettes, vaping products and tobacco heating products on oxidative stress

R Emma, M Caruso, D Campagna, R Pulvirenti… - Antioxidants, 2022 - mdpi.com
Cells constantly produce oxidizing species because of their metabolic activity, which is
counteracted by the continuous production of antioxidant species to maintain the …

New frontiers in the treatment of comorbid cardiovascular disease in chronic obstructive pulmonary disease

K Brassington, S Selemidis, S Bozinovski… - Clinical …, 2019 - portlandpress.com
Chronic obstructive pulmonary disease (COPD) is a disease characterised by persistent
airflow limitation that is not fully reversible and is currently the fourth leading cause of death …