Crooked tail (Cd) mice bear a gain-of-function mutation in Lrp6, a co-receptor for canonical
WNT signaling, and are a model of neural tube defects (NTDs), preventable with dietary folic …

Background Meningomyelocele (MM) results from lack of closure of the neural tube during
embryologic development. Periconceptional folic acid supplementation is a modifier of MM …

During the last decades, endocrine-disrupting chemicals (EDCs) have attracted the attention
of the scientific community, as a result of a deepened understanding of their effects on …

Neural tube defects (NTDs) are one of the most common types of birth defects with a
complex etiology. We have previously profiled serum metabolites of pregnant women in …

Folate supplementation prevents up to 70% of neural tube defects (NTDs), which result from
a failure of neural tube closure during embryogenesis. The elucidation of the mechanisms …

Background: Neural tube defects (NTDs) consist of a variety of central nervous system
abnormalities, most of which result from a lack of closure of the neural tube. Aims and …

After a review of Arthur Benton's conceptual and methodological contributions to the
understanding of normal and pathological development, we discuss agenesis of the corpus …

Abstract Objective Neural tube defects (NTDs) are one of the most common congenital
anomalies caused by a complex interaction of many genetic and environmental factors. In …

Background Previous reports on the prevalence of neural tube defects (NTDs) in China did
not include cases of NTDs that were less than 28 weeks of gestational age (GA) and hence …

Scope Fumonisin B 1 (FB 1) is found in corn‐based foods and is a possible risk factor for
neural tube defects (NTDs). The mechanism (s) underlying NTD induction by FB 1 in LM/B c …