Hydrogels for RNA delivery

R Zhong, S Talebian, BB Mendes, G Wallace… - Nature materials, 2023 - nature.com
RNA-based therapeutics have shown tremendous promise in disease intervention at the
genetic level, and some have been approved for clinical use, including the recent COVID-19 …

Review of a new bone tumor therapy strategy based on bifunctional biomaterials

J Liao, R Han, Y Wu, Z Qian - Bone research, 2021 - nature.com
Bone tumors, especially those in osteosarcoma, usually occur in adolescents. The standard
clinical treatment includes chemotherapy, surgical therapy, and radiation therapy …

Neutrophil hitchhiking for drug delivery to the bone marrow

Z Luo, Y Lu, Y Shi, M Jiang, X Shan, X Li… - Nature …, 2023 - nature.com
Pharmaceuticals have been developed for the treatment of a wide range of bone diseases
and disorders, but suffer from problematic delivery to the bone marrow. Neutrophils are …

Engineered macrophages as near-infrared light activated drug vectors for chemo-photodynamic therapy of primary and bone metastatic breast cancer

Y Huang, Z Guan, X Dai, Y Shen, Q Wei, L Ren… - Nature …, 2021 - nature.com
Patients with primary and bone metastatic breast cancer have significantly reduced survival
and life quality. Due to the poor drug delivery efficiency of anti-metastasis therapy and the …

Pathological mechanism of photodynamic therapy and photothermal therapy based on nanoparticles

Y Hou, X Yang, R Liu, D Zhao, C Guo… - International journal …, 2020 - Taylor & Francis
The ultimate goal of phototherapy based on nanoparticles, such as photothermal therapy
(PTT) which generates heat and photodynamic therapy (PDT) which not only generates …

Current trends in smart mesoporous silica-based nanovehicles for photoactivated cancer therapy

K Wang, J Lu, J Li, Y Gao, Y Mao, Q Zhao… - Journal of Controlled …, 2021 - Elsevier
Photoactivated therapeutic strategies (photothermal therapy and photodynamic therapy),
due to the adjusted therapeutic area, time and light dosage, have prevailed for the fight …

Tumor acidity and near‐infrared light responsive dual drug delivery polydopamine‐based nanoparticles for chemo‐photothermal therapy

R Fan, C Chen, H Hou, D Chuan, M Mu… - Advanced Functional …, 2021 - Wiley Online Library
Photothermal therapy (PTT) combined with chemotherapy, a promising strategy for breast
cancer treatment, has a high potential to control drug release, reduce multidrug resistance …

Targeting nanoparticles for diagnosis and therapy of bone tumors: Opportunities and challenges

X Gao, L Li, X Cai, Q Huang, J Xiao, Y Cheng - Biomaterials, 2021 - Elsevier
A variety of targeted nanoparticles were developed for the diagnosis and therapy of
orthotopic and metastatic bone tumors during the past decade. This critical review will focus …

[HTML][HTML] The progress and perspective of nanoparticle-enabled tumor metastasis treatment

W Zhang, F Wang, C Hu, Y Zhou, H Gao… - Acta pharmaceutica sinica …, 2020 - Elsevier
As one of the most serious threats to human being, cancer is hard to be treated when
metastasis happens. What's worse, there are few identified targets of metastasis for drug …

Antibacterial hybrid hydrogels

Z Cao, Y Luo, Z Li, L Tan, X Liu, C Li… - Macromolecular …, 2021 - Wiley Online Library
Bacterial infectious diseases and bacterial‐infected environments have been threatening
the health of human beings all over the world. In view of the increased bacteria resistance …