[HTML][HTML] Interplay of chemokines receptors, toll-like receptors, and host immunological pathways

YT Chu, MT Liao, KW Tsai, KC Lu, WC Hu - Biomedicines, 2023 - mdpi.com
A comprehensive framework has been established for understanding immunological
pathways, which can be categorized into eradicated and tolerable immune responses. Toll …

[HTML][HTML] A comprehensive approach to developing a multi-epitope vaccine against Mycobacterium tuberculosis: from in silico design to in vitro immunization …

F Jiang, Y Han, Y Liu, Y Xue, P Cheng, L Xiao… - Frontiers in …, 2023 - frontiersin.org
Introduction The Bacillus Calmette-Guérin (BCG) vaccine, currently used against
tuberculosis (TB), exhibits inconsistent efficacy, highlighting the need for more potent TB …

[HTML][HTML] A novel 3D biofabrication strategy to improve cell proliferation and differentiation of human Wharton's jelly mesenchymal stromal cells for cell therapy and …

C Blanco-Elices, RI Oruezabal… - … in Bioengineering and …, 2023 - frontiersin.org
Purpose: Obtaining sufficient numbers of cells in a short time is a major goal of cell culturing
in cell therapy and tissue engineering. However, current bidimensional (2D) culture methods …

[HTML][HTML] Adipose tissue-derived mesenchymal stromal cells attenuate acute lung injury induced by trauma and haemorrhagic shock

Z Zhang, X Yang, Q Meng, Y Long, X Shi, Y Wang - Immunobiology, 2023 - Elsevier
Abstract Background Mesenchymal stromal cells (MSCs) have shown promising therapeutic
options for acute lung injury (ALI) caused by multiple factors. Here, we evaluated the …

[HTML][HTML] Interleukin-10 gene intervention ameliorates liver fibrosis by enhancing the immune function of natural killer cells in liver tissue

Y Chen, Y Huang, R Huang, Z Chen, X Wang… - International …, 2024 - Elsevier
Background and aims Interleukin 10 (IL-10) and natural killer (NK) cells have the potential to
combat liver fibrosis. However, whether NK cells play an important role in the anti-fibrotic …

[HTML][HTML] Nebulized glycyrrhizin/enoxolone drug modulates IL-17A in COVID-19 patients: a randomized clinical trial

U Zendejas-Hernandez, N Alcántara-Martínez… - Frontiers in …, 2024 - frontiersin.org
Introduction Glycyrrhizin (GA) and its derivative Enoxolone (18β), isolated from the
Glycyrrhiza glabra plant, are two potential molecules for treating viral diseases. Both …

Roles of telocytes dominated cell–cell communication in fibroproliferative acute respiratory distress syndrome

Y Zheng, S Cai, Z Zhao, X Wang… - Clinical and …, 2024 - Wiley Online Library
Telocytes (TCs) are a new type of interstitial cell identified in multiple tissues of mammals,
including the human lung, and mediate homocellular or heterocellular cell‐cell …

Lipid Nanoparticle-Associated Inflammation is Triggered by Sensing of Endosomal Damage: Engineering Endosomal Escape without Side Effects

S Omo-Lamai, Y Wang, MN Patel, E Essien, M Shen… - bioRxiv, 2024 - biorxiv.org
Lipid nanoparticles (LNPs) have emerged as the dominant platform for RNA delivery, based
on their success in the COVID-19 vaccines and late-stage clinical studies in other …

Types of Cell Death and Their Relations to Host Immunological Pathways

WC Hu - 2024 - preprints.org
Host immunological pathways have been proposed including TH1, TH2, TH3, TH9, TH17,
TH22, TH1-like, and THαβ immune reactions. Besides TH2 and TH9 immune responses …

TGFβ Producing Regulatory T Cells Related Tolerable Immunities and Their Relations to Scleroderma and End Organ Failures Including Heart Failure, Liver Cirrhosis …

WC Hu - 2024 - preprints.org
Regulatory T cells are key immune cells to initiate tolerable immune responses. TGFβ is the
key cytokine of regulatory T cells. TGFβ is also the master cytokine to stimulate tissue …