[HTML][HTML] Combined oral contraceptives and venous thromboembolism: review and perspective to mitigate the risk

L Morimont, H Haguet, JM Dogné, U Gaspard… - Frontiers in …, 2021 - frontiersin.org
Many factors must be considered and discussed with women when initiating a contraceptive
method and the risk of venous thromboembolism (VTE) is one of them. In this review, we …

[HTML][HTML] 2021 update of the International Council for Standardization in Haematology recommendations for laboratory measurement of direct oral anticoagulants

J Douxfils, DM Adcock, SM Bates… - Thrombosis and …, 2021 - thieme-connect.com
In 2018, the International Council for Standardization in Haematology (ICSH) published a
consensus document providing guidance for laboratories on measuring direct oral …

Low thrombin generation in users of a contraceptive containing estetrol and drospirenone

L Morimont, M Jost, U Gaspard… - The Journal of …, 2023 - academic.oup.com
Objective To compare the impact on thrombin generation of the new combined oral
contraceptive containing 15 mg estetrol and 3 mg drospirenone with ethinylestradiol (30 or …

A novel estetrol-containing combined oral contraceptive: European expert panel review

K Gemzell-Danielsson, A Cagnacci… - … European Journal of …, 2022 - Taylor & Francis
Purpose Despite considerable advances in recently developed combined oral
contraceptives (COCs), resulting in lower rates of adverse events while maintaining …

Impact of estetrol (E4) on hemostasis, metabolism and bone turnover in postmenopausal women

J Douxfils, U Gaspard, M Taziaux, M Jost, C Bouvy… - …, 2023 - Taylor & Francis
Objective This study aimed to determine the effects of estetrol (E4) on hemostasis, lipids,
carbohydrate metabolism and bone turnover in postmenopausal women. Methods This …

[HTML][HTML] Gender Medicine: A New Possible Frontiers of Venous Thromboembolism

T Ciarambino, P Crispino, O Para, M Giordano - Stresses, 2023 - mdpi.com
From the data in our possession derived from the literature, it has been shown that men
have a high risk and appear to have a specific higher risk of suffering from thromboembolism …

Evaluation of activated protein C resistance using thrombin generation test

J Douxfils, C Bouvy, L Morimont - Hemostasis and Thrombosis: Methods …, 2023 - Springer
Activated protein C (APC) resistance (APCR) has been identified as a risk factor of venous
thromboembolism (VTE). A mutation at the level of factor (F) V has at first permitted the …

Laboratory testing for the evaluation of phenotypic activated protein C resistance

L Morimont, N Donis, C Bouvy, F Mullier… - … in thrombosis and …, 2022 - thieme-connect.com
Activated protein C (APC) resistance (APCR) is considered a risk factor of venous
thromboembolism (VTE). The most common genetic disorder conferring APCR is a factor (F) …

[HTML][HTML] The effect of hormonal contraceptive therapy on clinical laboratory parameters: a literature review

Ö Özcan, WPJ den Elzen, JJ Hillebrand… - Clinical Chemistry and …, 2024 - degruyter.com
Hormonal contraceptives (HC) are widely used among women in reproductive ages. In this
review, the effects of HCs on 91 routine chemistry tests, metabolic tests, and tests for liver …

[PDF][PDF] Estetrol is not a SERM but a NEST and has a specific safety profile on coagulation

J Douxfils, L Morimont, U Gaspard… - Thrombosis …, 2023 - researchportal.unamur.be
We read with interest the article of Booyens et al. discussing the risk of venous
thromboembolism (VTE) with hormonal replacement therapy (HRT)[1]. This article nicely …