Abstract Background The Global Polio Eradication Initiative introduced novel oral polio
vaccine Type 2 (nOPV2) to address circulating vaccine-derived poliovirus Type 2 (cVDPV2) …

To assess circulation of the Sabin 2 poliovirus vaccine strain in Madagascar after its
withdrawal from the oral polio vaccine in April 2016, a reinforced poliovirus surveillance was …

Following the global declaration of indigenous wild poliovirus type 2 eradication in 2015, the
world switched to oral polio vaccine (OPV) that removed the type 2 component. This …

Now, more than 20 years after the initial target for polio eradication, the Global Polio
Eradication Initiative (GPEI) remains off track in its mission to stop and prevent the …

In 2011, a dedicated consortium of experts commenced work on the development of the
novel oral poliovirus vaccine type 2 (nOPV2). After careful and rigorous analysis of data to …

Poliomyelitis is an exclusively human disease that mainly affects children. Clinical features
of poliomyelitis can be varied, from mild illness to the most severe paralysis, and the factor …

Background: The polio eradication endgame continues to increase in complexity. With polio
cases caused by wild poliovirus type 1 and circulating vaccine-derived polioviruses of all …

A poliomielite é uma doença sem cura, causada por poliovírus, mas prevenível através da
vacinação. A infeção pode não afetar o sistema nervoso central (SNC), levando a doença …

Background: Circulating vaccine derived poliovirus (cVDPV) outbreaks remain a threat to
polio eradication. To reduce cases of polio from cVDPV of serotype 2, the serotype 2 …

Acute anterior poliomyelitis was recognized as a clinical entity in the late nineteenth century,
and was shown to be caused by a virus in the early twentieth century. Initially, it was …