Plasmodium vivax is the most widespread human malaria, putting 2.5 billion people at risk of
infection. Its unique biological and epidemiological characteristics pose challenges to …

Antimalarial drugs are key tools for the control and elimination of malaria. Recent decreases
in the global malaria burden are likely due, in part, to the deployment of artemisinin-based …

Background Primaquine is a key drug for malaria elimination. In addition to being the only
drug active against the dormant relapsing forms of Plasmodium vivax, primaquine is the sole …

Abstract Glucose-6-phosphate dehydrogenase (G6PD) is a potentially pathogenic inherited
enzyme abnormality and, similar to other human red blood cell polymorphisms, is …

P. cynomolgi, a malaria-causing parasite of Asian Old World monkeys, is the sister taxon of
P. vivax, the most prevalent malaria-causing species in humans outside of Africa. Because …

The technical genesis and practice of 8-aminoquinoline therapy of latent malaria offer
singular scientific, clinical, and public health insights. The 8-aminoquinolines brought …

The diagnosis and treatment of Plasmodium vivax malaria differs from that of Plasmodium
falciparum malaria in fundamentally important ways. This article reviews the guiding …

Background Endemic malaria occurring across much of the globe threatens millions of
exposed travelers. While unknown numbers of them suffer acute attacks while traveling …

Background: Malaria is one of the infectious diseases of greatest interest to the scientific
community and of greatest concern to international health authorities. Traditionally, the focus …

Aggregation of α-synuclein (α-Syn) into toxic oligomers and fibrils leads to Parkinson's
disease (PD) pathogenesis. Molecules that can inhibit the fibrillization and oligomerization …