Endosomes are central protein-sorting stations at the crossroads of numerous membrane
trafficking pathways in all eukaryotes. They have a key role in protein homeostasis and …

Membrane lipids play vital roles in small extracellular vesicle (sEV) biogenesis. However,
the function of various lipids in the biogenesis of sEVs is still poorly understood …

Endosomal cargo recycling lies at the heart of subcellular trafficking processes under the
management of several Rasrelated GTPbinding proteins (Rabs) which are coordinated by …

Formation and fission of tubules from autolysosomes, endolysosomes, or phagolysosomes
are required for lysosome reformation. However, the mechanisms governing these …

Melanosomes are pigment cell-specific lysosome-related organelles in which melanin
pigments are synthesized and stored. Melanosome maturation requires delivery of …

In eukaryotes, the spatiotemporal control of endolysosomal organelles is central to the
maintenance of homeostasis. By providing an interface between the cytoplasm and external …

Uric acid is the end-product of nitrogen metabolism of the silkworm and other lepidopterans.
The accumulation of uric acid particles in the epidermis causes the larval silkworm to appear …

Phagocytosis: Phagolysosome vesiculation promotes cell corpse degradation: Current Biology
Skip to Main Content Advertisement Current Biology This journal offers authors two options …

Exosomes are small extracellular vesicles that are enriched in specific proteins and lipids
during their generation as intraluminal vesicles in multivesicular endosomes. Contrary to …

The major organelles and pathways of the endomembrane system were in place by the time
of the last eukaryotic common ancestor (LECA)(~ 1.5 billion years ago) and their acquisition …