[HTML][HTML] The emerging role of extracellular vesicles in fungi: A double-edged sword

Y Lai, B Jiang, F Hou, X Huang, B Ling, H Lu… - Frontiers in …, 2023 - frontiersin.org
Fungi are eukaryotic microorganisms found in nature, which can invade the human body
and cause tissue damage, inflammatory reactions, organ dysfunctions, and diseases. These …

“We've got to get out”—Strategies of human pathogenic fungi to escape from phagocytes

J Sonnberger, L Kasper, T Lange… - Molecular …, 2024 - Wiley Online Library
Human fungal pathogens are a deadly and underappreciated risk to global health that most
severely affect immunocompromised individuals. A virulence attribute shared by some of the …

[HTML][HTML] Exploring extracellular vesicles of probiotic yeast as carriers of biologically active molecules transferred to human intestinal cells

J Mierzejewska, P Kowalska, K Marlicka… - International Journal of …, 2023 - mdpi.com
Extracellular vesicles (EVs) are nanoparticles containing various bioactive cargos—eg,
proteins, RNAs, and lipids—that are released into the environment by all cell types. They are …

Fungal mechanisms of intracellular survival: what can we learn from bacterial pathogens?

PV Stuckey, FH Santiago-Tirado - Infection and Immunity, 2023 - Am Soc Microbiol
Fungal infections represent a major, albeit neglected, public health threat with serious
medical and economic burdens globally. With unacceptably high mortality rates, invasive …

[HTML][HTML] Bet-hedging antimicrobial strategies in macrophage phagosome acidification drive the dynamics of Cryptococcus neoformans intracellular escape …

Q Dragotakes, E Jacobs, LS Ramirez, OI Yoon… - PLoS …, 2022 - journals.plos.org
The fungus Cryptococcus neoformans is a major human pathogen with a remarkable
intracellular survival strategy that includes exiting macrophages through non-lytic exocytosis …

[HTML][HTML] Inhibition of Microbicidal Activity of Canine Macrophages DH82 Cell Line by Capsular Polysaccharides from Cryptococcus neoformans

IF LaRocque-de-Freitas, EB da Silva-Junior… - Journal of Fungi, 2024 - mdpi.com
Cryptococcus neoformans is a lethal fungus that primarily affects the respiratory system and
the central nervous system. One of the main virulence factors is the capsule, constituted by …