Exercise and epigenetic inheritance of disease risk

J Denham - Acta Physiologica, 2018 - Wiley Online Library
Epigenetics is the study of gene expression changes that occur in the absence of altered
genotype. Current evidence indicates a role for environmentally induced alterations to …

Exercise alters mouse sperm small noncoding RNAs and induces a transgenerational modification of male offspring conditioned fear and anxiety

AK Short, S Yeshurun, R Powell, VM Perreau… - Translational …, 2017 - nature.com
There is growing evidence that the preconceptual lifestyle and other environmental
exposures of a father can significantly alter the physiological and behavioral phenotypes of …

[HTML][HTML] Maternal exercise during pregnancy promotes physical activity in adult offspring

JD Eclarinal, S Zhu, MS Baker, DB Piyarathna… - The FASEB …, 2016 - ncbi.nlm.nih.gov
Previous rodent studies have shown that maternal voluntary exercise during pregnancy
leads to metabolic changes in adult offspring. We set out to test whether maternal voluntary …

Exercise during pregnancy and its impact on mothers and offspring in humans and mice

N Ferrari, I Bae-Gartz, C Bauer… - … origins of health and …, 2018 - cambridge.org
Exercise during pregnancy has beneficial effects on maternal and offspring's health in
humans and mice. The underlying mechanisms remain unclear. This comparative study …

Maternal exposure to Western diet affects adult body composition and voluntary wheel running in a genotype-specific manner in mice

L Hiramatsu, JC Kay, Z Thompson, JM Singleton… - Physiology & …, 2017 - Elsevier
Some human diseases, including obesity, Type II diabetes, and numerous cancers, are
thought to be influenced by environments experienced in early life, including in utero …

Maternal exercise during pregnancy modulates genotoxicity caused by high fructose consumption in mice offspring

ML Magenis, AP Damiani, IO Monteiro… - …, 2024 - academic.oup.com
Pregnancy is a period that is characterized by several metabolic and physiological changes
and requires special attention, especially with regard to the relationship between feeding …

Involuntary swimming exercise in pregnant rats disturbs ERK1/2 signaling in embryonic neurons through increased cortisol in the amniotic fluid

Y Jang, B Lee, EK Kim, WS Shim, YD Yang… - … and biophysical research …, 2018 - Elsevier
Harmful maternal behaviors, such as drinking and smoking, negatively affect embryonic
development. In contrast, regular maternal exercise is believed to be beneficial to the fetus …

Pregnancy swimming prevents early brain mitochondrial dysfunction and causes sex-related long-term neuroprotection following neonatal hypoxia-ischemia in rats

EF Sanches, TM Dos Santos, F Odorcyk… - Experimental …, 2021 - Elsevier
Neonatal hypoxia-ischemia (HI) is a major cause of cognitive impairments in infants.
Antenatal strategies improving the intrauterine environment can have high impact …

Effects of maternal controlled exercise on offspring adiposity and glucose tolerance

KM Platt, J Przybylowski, RJ Charnigo… - … origins of health and …, 2022 - cambridge.org
While metabolic disorders such as obesity and diabetes are costly and deadly to the current
population, they are also extremely detrimental to the next generation. Much of the current …

Wheel-running exercise before and during gestation against acute and sensitized cocaine psychomotor-activation in offspring

LF Lespine, A Plenevaux, E Tirelli - Behavioural Brain Research, 2019 - Elsevier
While animal research has consistently reported preventive effects of exercise against drug
abuse vulnerability, little is known about the influence of the developmental stage during …