Intravoxel incoherent motion diffusion-weighted MRI of infiltrated marrow for predicting overall survival in newly diagnosed acute myeloid leukemia

J Li, W Li, J Niu, X Song, W Wu, T Gong, R Zheng… - Radiology, 2020 - pubs.rsna.org
Background Acute myeloid leukemia (AML) features relatively low overall survival (OS).
Intravoxel incoherent motion (IVIM) diffusion-weighted MRI separates tissue microcapillary …

Memory T cells skew toward terminal differentiation in the CD8+ T cell population in patients with acute myeloid leukemia

L Xu, D Yao, J Tan, Z He, Z Yu, J Chen, G Luo… - Journal of Hematology & …, 2018 - Springer
Stem cell memory T (T SCM) and central memory T (T CM) cells can rapidly differentiate into
effector memory (T EM) and terminal effector (T EF) T cells, and have the most potential for …

Immune-based therapeutic strategies for acute myeloid leukemia

M Böhme, S Kayser - Cancers, 2021 - mdpi.com
Simple Summary This review summarizes various therapeutic immune approaches
representing their targets, the efficacy and toxicity in the treatment of acute myeloid …

Shifting paradigms in the treatment of older adults with AML

TW LeBlanc, HP Erba - Seminars in Hematology, 2019 - Elsevier
The treatment of acute myeloid leukemia has been associated with dismal outcomes despite
available therapies. The morbidity and mortality associated with acute myeloid leukemia …

Chemotherapeutic drugs elicit stemness and metabolic alteration to mediate acquired drug-resistant phenotype in acute myeloid leukemia cell lines

RSS Illangeswaran, DZP Jebanesan, KK Sivakumar… - Leukemia Research, 2023 - Elsevier
Chemotherapy resistance leading to disease relapse is a significant barrier in treating acute
myeloid leukemia (AML). Metabolic adaptations have been shown to contribute to therapy …

High CRP-albumin ratio predicts poor prognosis in transplant ineligible elderly patients with newly diagnosed acute myeloid leukemia

H Senjo, M Onozawa, D Hidaka, S Yokoyama… - Scientific reports, 2022 - nature.com
Acute myeloid leukemia (AML) patients older than 65 years have a poor prognosis.
Recently, CAR (C-reactive-protein/albumin ratio) has been actively reported as a prognostic …

[HTML][HTML] Comparable outcomes after alternative and matched sibling donor hematopoietic stem cell transplantation and the role of molecular measurable residual …

BS Cho, SA Yahng, GJ Min, S Park, SS Park… - … and Cellular Therapy, 2021 - Elsevier
Allogeneic hematopoietic stem cell transplantation (HSCT) remains the most effective
postremission therapy conferring the chance of cure for acute myeloid leukemia (AML) …

Low‐dose thymoglobulin for prevention of chronic graft‐versus‐host disease in transplantation from an HLA‐matched sibling donor

BS Cho, GJ Min, SS Park, SY Yoon… - American Journal of …, 2021 - Wiley Online Library
Despite the proven efficacy of anti‐T‐cell or antithymocyte globulin (ATG) for chronic graft‐
versus‐host disease (GVHD) prevention in transplantation from an unrelated donor, dosing …

FLT3-TKD in the prognosis of patients with acute myeloid leukemia: a meta-analysis

S Li, N Li, Y Chen, Z Zheng, Y Guo - Frontiers in Oncology, 2023 - frontiersin.org
Background Fms-like tyrosine kinase 3 (FLT3) gene mutations occur in approximately 30%
of all patients with acute myeloid leukemia (AML). Internal tandem duplication (ITD) in the …

Efficacy and safety of quizartinib in Japanese patients with FLT3-ITD positive relapsed or refractory acute myeloid leukemia in an open-label, phase 2 study

T Takahashi, K Usuki, K Matsue, H Ohno… - International Journal of …, 2019 - Springer
FMS-like tyrosine kinase 3 (FLT3) internal tandem duplication (ITD) mutations in patients
with acute myeloid leukemia (AML) are associated with early relapse and poor survival. This …