[HTML][HTML] The epidemiology, treatment patterns, healthcare utilizations and costs of Acute Myeloid Leukaemia (AML) in Taiwan

HH Huang, CM Chen, CY Wang, WWY Hsu, HM Chen… - PloS one, 2022 - journals.plos.org
Backgrounds An increasing incidence of Acute Myeloid Leukaemia (AML) has been
reported in several Western countries. However, the epidemiology of AML in Asia is very …

A retrospective study of comorbidities and complications in elderly acute myeloid leukemia patients in the United States

N Dhopeshwarkar, S Iqbal, X Wang, M Salas - … Lymphoma Myeloma and …, 2019 - Elsevier
Background Comorbidities in acute myeloid leukemia (AML) patients have been shown to
increase with age. However, few studies have described the disease burden in elderly AML …

[HTML][HTML] At what point are long-term (> 5 years) survivors of APL safe? A study from the SEER database

XJ Yin, R Wang, HS Shen, J Jin, HH Zhu - Cancers, 2023 - mdpi.com
Simple Summary The history of the treatment of APL has shown remarkable success.
However, it is not clear whether it is necessary to monitor long-term toxicity in “cured” …

A 2: 1 randomized, open-label, phase II study of selinexor vs. physician's choice in older patients with relapsed or refractory acute myeloid leukemia

K Sweet, B Bhatnagar, H Döhner… - Leukemia & …, 2021 - Taylor & Francis
Selinexor, a selective inhibitor of nuclear export, has demonstrated promising activity in
patients with acute myeloid leukemia (AML). This randomized, phase II study evaluated …

[HTML][HTML] Identification of CD318 (CDCP1) as novel prognostic marker in AML

JS Heitmann, I Hagelstein, C Hinterleitner… - Annals of …, 2020 - Springer
Genetic and morphological markers are well-established prognostic factors in acute myeloid
leukemia (AML). However, further reliable markers are urgently needed to improve risk …

Prognostic value of hypoalbuminemia at diagnosis in de novo non-M3 acute myeloid leukemia

N Wang, A Desai, B Ge, W Li, X Jin, H Bai… - Leukemia & …, 2020 - Taylor & Francis
The association between serum albumin level and clinical outcomes has been reported for
several hematological malignancies. Our study aimed to identify the relationship between …

[HTML][HTML] Association of mutations with morphological dysplasia in de novo acute myeloid leukemia without 2016 WHO Classification-defined cytogenetic abnormalities

OK Weinberg, CJ Gibson, TM Blonquist… - …, 2018 - ncbi.nlm.nih.gov
Despite improvements in our understanding of the molecular basis of acute myeloid
leukemia (AML), the association between genetic mutations with morphological dysplasia …

[HTML][HTML] Unveiling the methyl transfer mechanisms in the epigenetic machinery DNMT3A-3 L: A comprehensive study integrating assembly dynamics with catalytic …

W Yang, J Zhuang, C Li, GJ Cheng - Computational and Structural …, 2023 - Elsevier
In epigenetic mechanisms, DNA methyltransferase 3 alpha (DNMT3A) acts as an initiator for
DNA methylation and prevents the downstream genes from expressing. Perturbations of …

Challenges and opportunities in the assessment of measurable residual disease in multiple myeloma

S Bal, A Weaver, RF Cornell… - British journal of …, 2019 - Wiley Online Library
Treatment response assessment in multiple myeloma (MM) relies on the detection of
paraprotein in serum and/or urine, bone marrow morphology and immunohistochemistry …

Acute myeloid leukemia treatment in the elderly: a comprehensive review of the present and future

J Choi, M Shukla, M Abdul-Hay - Acta Haematol, 2023 - karger.com
Background: Acute myeloid leukemia (AML) is a disease of the hematopoietic system that
remains a therapeutic challenge despite advances in our understanding of the underlying …