Chondroitin sulfates and their binding molecules in the central nervous system

L Djerbal, H Lortat-Jacob, JCF Kwok - Glycoconjugate journal, 2017 - Springer
Chondroitin sulfate (CS) is the most abundant glycosaminoglycan (GAG) in the central
nervous system (CNS) matrix. Its sulfation and epimerization patterns give rise to different …

Proteoglycans in dentinogenesis

G Embery, R Hall, R Waddington… - Critical Reviews in …, 2001 - journals.sagepub.com
The predominant proteoglycans present in predentin and dentin are the chondroitin-
sulphate-rich decorin and biglycan and the keratan-sulphate-rich lumican and fibromodulin …

Specific molecular interactions of oversulfated chondroitin sulfate E with various heparin-binding growth factors: implications as a physiological binding partner in the …

SS Deepa, Y Umehara, S Higashiyama, N Itoh… - Journal of Biological …, 2002 - ASBMB
We previously observed that the cortical neuronal cell adhesion mediated by midkine (MK),
a heparin (Hep)-binding growth factor, is specifically inhibited by oversulfated chondroitin …

The DSD-1 carbohydrate epitope depends on sulfation, correlates with chondroitin sulfate D motifs, and is sufficient to promote neurite outgrowth

AM Clement, S Nadanaka, K Masayama… - Journal of Biological …, 1998 - ASBMB
The neural chondroitin sulfate (CS) proteoglycan (PG) DSD-1-PG was originally identified
with the monoclonal antibody (mAb) 473HD. It promotes neurite outgrowth of hippocampal …

Molecular cloning and characterization of a human uronyl 2-sulfotransferase that sulfates iduronyl and glucuronyl residues in dermatan/chondroitin sulfate

M Kobayashi, G Sugumaran, J Liu, NW Shworak… - Journal of biological …, 1999 - ASBMB
A partial-length human cDNA with a predicted amino acid sequence homologous to a
previously described heparan sulfate iduronyl 2-sulfotransferase (Kobayashi, M., Habuchi …

Characteristic hexasaccharide sequences in octasaccharides derived from shark cartilage chondroitin sulfate D with a neurite outgrowth promoting activity

S Nadanaka, A Clement, K Masayama… - Journal of Biological …, 1998 - ASBMB
A mouse brain chondroitin sulfate (CS) proteoglycan, DSD-1-PG, bears the DSD-1 epitope
and has neurite outgrowth promoting properties. Shark cartilage CS-C inhibits the …

Structural and functional characterization of oversulfated chondroitin sulfate/dermatan sulfate hybrid chains from the notochord of hagfish: Neuritogenic and binding …

CD Nandini, T Mikami, M Ohta, N Itoh… - Journal of Biological …, 2004 - ASBMB
Oversulfated chondroitin sulfate (CS)/dermatan sulfate (DS) hybrid chains were purified from
the notochord of hagfish. The chains (previously named CS-H for hagfish) have an average …

Structural characterization of the epitopes of the monoclonal antibodies 473HD, CS-56, and MO-225 specific for chondroitin sulfate D-type using the oligosaccharide …

Y Ito, M Hikino, Y Yajima, T Mikami, S Sirko… - …, 2005 - academic.oup.com
The variation in the sulfation profile of chondroitin sulfate (CS)/dermatan sulfate (DS) chains
regulates central nervous system development in vertebrates. Notably, the disulfated …

Regulation of glycan structures in murine embryonic stem cells: combined transcript profiling of glycan-related genes and glycan structural analysis

AV Nairn, K Aoki, M dela Rosa, M Porterfield… - Journal of Biological …, 2012 - ASBMB
The abundance and structural diversity of glycans on glycoproteins and glycolipids are
highly regulated and play important roles during vertebrate development. Because of the …

Sulfated glycosaminoglycans support osteoblast functions and concurrently suppress osteoclasts

J Salbach‐Hirsch, N Ziegler, S Thiele… - Journal of cellular …, 2014 - Wiley Online Library
In order to improve bone regeneration, development and evaluation of new adaptive
biomaterials is warranted. Glycosaminoglycans (GAGs) such as hyaluronan (HA) and …