Artificial intelligence aids in development of nanomedicines for cancer management

P Tan, X Chen, H Zhang, Q Wei, K Luo - Seminars in cancer biology, 2023 - Elsevier
Over the last decade, the nanomedicine has experienced unprecedented development in
diagnosis and management of diseases. A number of nanomedicines have been approved …

Engineering microrobots for targeted cancer therapies from a medical perspective

CK Schmidt, M Medina-Sánchez… - Nature …, 2020 - nature.com
Systemic chemotherapy remains the backbone of many cancer treatments. Due to its
untargeted nature and the severe side effects it can cause, numerous nanomedicine …

Shattering barriers toward clinically meaningful MSC therapies

O Levy, R Kuai, EMJ Siren, D Bhere, Y Milton… - Science …, 2020 - science.org
More than 1050 clinical trials are registered at FDA. gov that explore multipotent
mesenchymal stromal cells (MSCs) for nearly every clinical application imaginable …

Foundations of gastrointestinal-based drug delivery and future developments

JN Chu, G Traverso - Nature Reviews Gastroenterology & Hepatology, 2022 - nature.com
Gastrointestinal-based drug delivery is considered the preferred mode of drug
administration owing to its convenience for patients, which improves adherence. However …

Macrophage cell membrane‐cloaked nanoplatforms for biomedical applications

J Lopes, D Lopes, M Pereira‐Silva, D Peixoto… - Small …, 2022 - Wiley Online Library
Biomimetic approaches utilize natural cell membrane‐derived nanovesicles to camouflage
nanoparticles to circumvent some limitations of nanoscale materials. This emergent cell …

Harnessing anti‐tumor and tumor‐tropism functions of macrophages via nanotechnology for tumor immunotherapy

Y Zheng, Y Han, Q Sun, Z Li - Exploration, 2022 - Wiley Online Library
Reprogramming the immunosuppressive tumor microenvironment by modulating
macrophages holds great promise in tumor immunotherapy. As a class of professional …

Tumour‐derived extracellular vesicle membrane hybrid lipid nanovesicles enhance siRNA delivery by tumour‐homing and intracellular freeway transportation

X Zhou, Y Miao, Y Wang, S He, L Guo… - Journal of …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) have been proved a promising small interfering RNA (siRNA)
delivery vehicle to mediate gene‐silencing. Tumour‐derived extracellular vesicles (TDEVs) …

Cell membrane coating technology: a promising strategy for biomedical applications

Y Liu, J Luo, X Chen, W Liu, T Chen - Nano-Micro Letters, 2019 - Springer
Cell membrane coating technology is an approach to the biomimetic replication of cell
membrane properties, and is an active area of ongoing research readily applicable to …

Improving cancer immunotherapy by cell membrane‐camouflaged nanoparticles

Z Zeng, K Pu - Advanced Functional Materials, 2020 - Wiley Online Library
Cancer immunotherapy has received tremendous attention in the past decade owing to its
clinical successes with the use of immune‐checkpoint inhibition and chimeric antigen …

[HTML][HTML] Cell membrane camouflaged biomimetic nanoparticles: Focusing on tumor theranostics

L Zhu, Y Zhong, S Wu, M Yan, Y Cao, N Mou, G Wang… - Materials Today Bio, 2022 - Elsevier
Nanoparticles (NPs) modified by cell membranes represent an emerging biomimetic
platform that can mimic the innate biological functions resulting from the various cell …