Krüppel-like factor 2 (KLF2) in immune cell migration

J Wittner, W Schuh - Vaccines, 2021 - mdpi.com
Krüppel-like factor 2 (KLF2), a transcription factor of the krüppel-like family, is a key regulator
of activation, differentiation, and migration processes in various cell types. In this review, we …

Deciphering the spectrum of cutaneous lymphomas expressing TFH markers

M Donzel, A Trecourt, B Balme, O Harou, C Mauduit… - Scientific Reports, 2023 - nature.com
T-follicular helper (TFH) markers are expressed in the microenvironnement of marginal zone
B-cell lymphoma (MZL), and in lymphomas arising from TFH-cells, sometimes making the …

NOTCH signaling in the pathogenesis of splenic marginal zone lymphoma—opportunities for therapy

JP Alderuccio, IS Lossos - Leukemia & lymphoma, 2022 - Taylor & Francis
NOTCH signaling is a highly conserved pathway mediated by four receptors (NOTCH 1–4)
playing critical functions in proliferation, differentiation, and cell death. Under physiologic …

Subtype-WGME enables whole-genome-wide multi-omics cancer subtyping

H Yang, L Zhao, D Li, C An, X Fang, Y Chen, J Liu… - Cell Reports …, 2024 - cell.com
We present an innovative strategy for integrating whole-genome-wide multi-omics data,
which facilitates adaptive amalgamation by leveraging hidden layer features derived from …

A t (4; 13)(q21; q14) translocation in B-cell chronic lymphocytic leukemia causing concomitant homozygous DLEU2/miR15a/miR16-1 and heterozygous ARHGAP24 …

D Tolomeo, A Agostini, AG Solimando, CL Cunsolo… - Cancer Genetics, 2023 - Elsevier
Abstract 13q14 deletion is the most recurrent chromosomal aberration reported in B-CLL,
having a favorable prognostic significance when occurring as the sole cytogenetic alteration …

Investigation of mutations, copy number variations and translocations by capture-based Next-generation sequencing in patients with chronic B-cell lymphoproliferative …

D Wren - 2021 - e-space.mmu.ac.uk
Patients with leukaemic indolent B-NHL who could not be assigned to a specific disease
category were identified and 108 cases underwent extensive molecular characterisation …