The use of plant secondary metabolites has gained considerable attention among clinicians
in the prevention and treatment of cancer. A secondary metabolite isolated mainly from the …

Human Papillomavirus (HPV)-6 and-11 are the causative agents of ano-genital warts (GWs)
and recurrent respiratory papillomatosis (RRP). They are low-risk HPV types that are …

The imidazoquinoline compounds imiquimod and R-848 are low-molecular-weight immune
response modifiers that can induce the synthesis of interferon-α and other cytokines in a …

Type I interferons (IFN) are well studied cytokines with anti-viral and immune-modulating
functions. Type I IFNs are produced following viral infections, but until recently, the …

External genital warts (EGWs) are visible warts that occur in the perigenital and perianal
regions. They are due primarily to non-oncogenic human papillomavirus (HPV) types …

The immune response modifiers, imiquimod and resiquimod, are TLR7 agonists that induce
type I interferon in numerous species, including humans. Recently, it was shown that …

The most common cause of mortality related to human papillomavirus (HPV) infection is
cervical cancer. However, male HPV infection is also an important concern, both for the …

Human papillomavirus (HPV) is the most common sexually transmitted virus in the world.
About 70% of cervical cancers are caused by the most oncogenic HPV genotypes of 16 and …

Rabbit oral papillomavirus (ROPV) causes benign and spontaneously regressing oral
lesions in rabbits, and is a useful model of disease associated with low-risk human …

Genital human papillomavirus (HPV) infection is very common, and often sub-clinical and
usually resolves without any treatment. Genital warts are caused by HPV 6/11 infection and …