Obesity and osteoarthritis, more than just wear and tear: pivotal roles for inflamed adipose tissue and dyslipidaemia in obesity-induced osteoarthritis
E Thijssen, A Van Caam, PM Van Der Kraan - Rheumatology, 2015 - academic.oup.com
OA is a degenerative joint disease characterized by articular cartilage degradation,
osteophyte formation, synovitis, and subchondral bone sclerosis. One of OAs main risk …
osteophyte formation, synovitis, and subchondral bone sclerosis. One of OAs main risk …
Associations between adipokines in arthritic disease and implications for obesity
Secretion from adipose tissue of adipokines or adipocytokines, comprising of bioactive
peptides or proteins, immune molecules and inflammatory mediators, exert critical roles in …
peptides or proteins, immune molecules and inflammatory mediators, exert critical roles in …
Evaluating the performance of 3D-printed PLA reinforced with date pit particles for its suitability as an acetabular liner in artificial hip joints
Off-the-shelf hip joints are considered essential parts in rehabilitation medicine that can help
the disabled. However, the failure of the materials used in such joints can cause individual …
the disabled. However, the failure of the materials used in such joints can cause individual …
Efficacy of mesenchymal stem cells in treating patients with osteoarthritis of the knee: A meta‑analysis
GH Cui, YY Wang, CJ Li… - Experimental and …, 2016 - spandidos-publications.com
To assess the clinical efficacy and safety of mesenchymal stem cell (MSC) treatment for
osteoarthritis of the knee (KOA), a systematic electronic literature search was performed on …
osteoarthritis of the knee (KOA), a systematic electronic literature search was performed on …
Obesity, exercise and orthopedic disease
CW Frye, JW Shmalberg… - Veterinary Clinics: Small …, 2016 - vetsmall.theclinics.com
Osteoarthritis, or degenerative joint disease, is characterized by a complex progressive
imbalance between cartilage production and degradation. The inciting biochemical cause of …
imbalance between cartilage production and degradation. The inciting biochemical cause of …
[HTML][HTML] Associations between knee structural measures, circulating inflammatory factors and MMP13 in patients with knee osteoarthritis
G Ruan, J Xu, K Wang, J Wu, Q Zhu, J Ren… - Osteoarthritis and …, 2018 - Elsevier
Objective To investigate cross-sectional associations between serum level of Matrix
metalloproteinase (MMP) 13 and knee structural measures and circulating inflammatory …
metalloproteinase (MMP) 13 and knee structural measures and circulating inflammatory …
An extensive review regarding the adipokines in the pathogenesis and progression of osteoarthritis
C Tu, J He, B Wu, W Wang, Z Li - Cytokine, 2019 - Elsevier
Osteoarthritis is the most prevalent form of aging-related joint diseases, and its etiology is
still not fully understood. Obesity has been recognized as one of the most significant and …
still not fully understood. Obesity has been recognized as one of the most significant and …
TNF‑α increases the expression of inflammatory factors in synovial fibroblasts by inhibiting the PI3K/AKT pathway in a rat model of monosodium iodoacetate‑induced …
H Li, S Xie, Y Qi, H Li, R Zhang… - Experimental and …, 2018 - spandidos-publications.com
Osteoarthritis is a degenerative disease that often causes patients to experience joint pain
and deformity. It has been demonstrated that tumor necrosis factor (TNF)‑α is associated …
and deformity. It has been demonstrated that tumor necrosis factor (TNF)‑α is associated …
Maslinic acid prevents IL‐1β‐induced inflammatory response in osteoarthritis via PI3K/AKT/NF‐κB pathways
YL Chen, DY Yan, CY Wu, JW Xuan… - Journal of Cellular …, 2021 - Wiley Online Library
Osteoarthritis (OA) is a degenerative joint disease characterized by destruction of articular
cartilage. The inflammatory response is the most important factor affecting the disease …
cartilage. The inflammatory response is the most important factor affecting the disease …
Infrapatellar fat pad-derived MSC response to inflammation and fibrosis induces an immunomodulatory phenotype involving CD10-mediated Substance P …
D Kouroupis, AC Bowles, MA Willman… - Scientific reports, 2019 - nature.com
The infrapatellar fat pad (IFP) serves as a reservoir of Mesenchymal Stem Cells (MSC), and
with adjacent synovium plays key roles in joint disease including the production of …
with adjacent synovium plays key roles in joint disease including the production of …