[HTML][HTML] Therapeutic promise of carotenoids as antioxidants and anti-inflammatory agents in neurodegenerative disorders
MT Kabir, MH Rahman, M Shah, MR Jamiruddin… - Biomedicine & …, 2022 - Elsevier
Abstract Neurodegenerative disorders (NDs) including Alzheimer's disease, Parkinson's
disease, amyotrophic lateral sclerosis, Huntington's disease, and multiple sclerosis have …
disease, amyotrophic lateral sclerosis, Huntington's disease, and multiple sclerosis have …
[HTML][HTML] Anti-oxidative, anti-inflammatory and anti-apoptotic effects of flavonols: targeting Nrf2, NF-κB and p53 pathways in neurodegeneration
Neurodegenerative diseases are one of the leading causes of disability and death
worldwide. Intracellular transduction pathways that end in the activation of specific …
worldwide. Intracellular transduction pathways that end in the activation of specific …
[HTML][HTML] Autophagy-lysosomal pathway as potential therapeutic target in Parkinson's disease
SR Bonam, C Tranchant, S Muller - Cells, 2021 - mdpi.com
Cellular quality control systems have gained much attention in recent decades. Among
these, autophagy is a natural self-preservation mechanism that continuously eliminates toxic …
these, autophagy is a natural self-preservation mechanism that continuously eliminates toxic …
[HTML][HTML] Linking ROS levels to autophagy: the key role of AMPK
F Agostini, M Bisaglia, N Plotegher - Antioxidants, 2023 - mdpi.com
Oxygen reactive species (ROS) are a group of molecules generated from the incomplete
reduction of oxygen. Due to their high reactivity, ROS can interact with and influence the …
reduction of oxygen. Due to their high reactivity, ROS can interact with and influence the …
Polymorphisms in genes related to oxidative stress and inflammation: Emerging links with the pathogenesis and severity of Cerebral Cavernous Malformation disease
A Perrelli, SF Retta - Free Radical Biology and Medicine, 2021 - Elsevier
Abstract Cerebral Cavernous Malformation (CCM) is a cerebrovascular disease of genetic
origin affecting 0.5% of the population and characterized by abnormally enlarged and leaky …
origin affecting 0.5% of the population and characterized by abnormally enlarged and leaky …
[HTML][HTML] Recent advances in cellular signaling interplay between redox metabolism and autophagy modulation in cancer: an overview of molecular mechanisms and …
Autophagy is a fundamental homeostatic process in which certain cellular components are
ingested by double-membrane autophagosomes and then degraded to create energy or to …
ingested by double-membrane autophagosomes and then degraded to create energy or to …
[HTML][HTML] Improving the treatment effect of carotenoids on Alzheimer's disease through various nano-delivery systems
W Su, W Xu, E Liu, W Su, NE Polyakov - International Journal of …, 2023 - mdpi.com
Natural bioactive compounds have recently emerged as a current strategy for Alzheimer's
disease treatment. Carotenoids, including astaxanthin, lycopene, lutein, fucoxanthin, crocin …
disease treatment. Carotenoids, including astaxanthin, lycopene, lutein, fucoxanthin, crocin …
scRNA-seq analysis reveals toxicity mechanisms in shrimp hemocytes subjected to nitrite stress
QJ Liang, BB Dong, A Li, LT Wu, Y Zhang, T Han, X Liu - Chemosphere, 2023 - Elsevier
In shrimp, hemocytes play an important role in detoxification and immune defense, and are
where nitrite accumulates during exposure to this toxic environmental pollutant. However …
where nitrite accumulates during exposure to this toxic environmental pollutant. However …
[HTML][HTML] A new glance at autophagolysosomal-dependent or-independent function of transcriptional factor EB in human cancer
T Wang, Y Qin, Z Ye, D Jing, G Fan, M Liu… - Acta Pharmacologica …, 2023 - nature.com
Autophagy-lysosome system plays a variety of roles in human cancers. In addition to being
implicated in metabolism, it is also involved in tumor immunity, remodeling the tumor …
implicated in metabolism, it is also involved in tumor immunity, remodeling the tumor …
[HTML][HTML] Essential Oil Molecules Can Break the Loop of Oxidative Stress in Neurodegenerative Diseases
E Spisni, MC Valerii, ML Massimino - Biology, 2023 - mdpi.com
Simple Summary Neurodegenerative diseases (NDs) affect millions of people worldwide.
The combination of genes and environment, associated with age, contributes to the risk of …
The combination of genes and environment, associated with age, contributes to the risk of …