Streptococcus mitis (S. mitis) is a pioneer commensal bacterial species colonizing many of
the surfaces of the oral cavity in healthy individuals. Yet, not much information is available …

Streptococcus pneumoniae is a bacterial pathogen that causes various diseases of public
health concern worldwide. Current pneumococcal vaccines target the capsular …

The vast majority of streptococci colonizing the human upper respiratory tract are
commensals, only sporadically implicated in disease. Of these, the most pathogenic is Mitis …

Purpose. Streptococcus oralis and Streptococcus mitis belong to the Mitis group, which are
mostly commensals in the human oral cavity. Even though S. oralis and S. mitis are oral …

Objective: Streptococcus mitis is a predominant oral colonizer, but difficulties in genetic
manipulation of this species have hampered our understanding of the mechanisms it uses …

S. mitis is an abundant member of the commensal microbiota of the oral cavity and pharynx,
which has the potential to promote systemic infections. By analyzing a collection of S. mitis …

Purpose. Mechanisms underlying systemic infections by oral species of Mitis (Streptococcus
mitis, Streptococcus oralis) and Sanguinis (Streptococcus gordonii, Streptococcus …

Bacteria utilize quorum sensing (QS) to coordinate many group behaviors. As such, QS has
attracted significant attention as a potential mean to attenuate bacterial infectivity without …

Both intracellular immune sensing and extracellular innate immune sensing have been
implicated in initiating macrophage proinflammatory cytokine responses to Streptococcus …

Streptococcus mitis colonizes all niches of the human oral cavity from early infancy and
throughout life. Monocytes patrol blood vessels, lymphoid and non‐lymphoid tissues and …