Antibiotic resistance is a major health concern globally and has been estimated to cause 10
million deaths worldwide by year 2050 if the current trend of inappropriate and excessive …

The advent of multidrug resistance among pathogenic bacteria is imperiling the worth of
antibiotics, which have previously transformed medical sciences. The crisis of antimicrobial …

The virulence factor database (VFDB, http://www. mgc. ac. cn/VFs/) is dedicated to
presenting a comprehensive knowledge base and a versatile analysis platform for bacterial …

Resistance to antimicrobial agents has become a major source of morbidity and mortality
worldwide. When antibiotics were first introduced in the 1900's, it was thought that we had …

Misuse and overuse of antibiotics have contributed in the last decades to a phenomenon
known as antibiotic resistance which is currently considered one of the principal threats to …

Fecal microbiota transplantation (FMT) is an emerging therapy for recurrent or refractory
Clostridioides difficile infection and is being actively investigated for other conditions. We …

Antimicrobial resistance (AMR) is a growing threat to human and animal health. Progress in
molecular biology has revealed new and significant challenges for AMR mitigation given the …

Chronic lung infection caused by bacterial biofilms is an extremely serious clinical problem,
which can lead to the failure of antibiotic therapy. Although nanoparticles have shown great …

Klebsiella pneumoniae is an important multidrug-resistant (MDR) pathogen affecting
humans and a major source for hospital infections associated with high morbidity and …

Bacteriophage (phage) therapy, ie, the use of viruses that infect bacteria as antimicrobial
agents, is a promising alternative to conventional antibiotics. Indeed, resistance to antibiotics …