Whole-genome sequencing (WGS) was used for the characterization of the frequently
extensively drug resistant (XDR) Pseudomonas aeruginosa sequence type 175 (ST175) …

Tigecycline is regarded as the last line of defense to combat multidrug-resistant Klebsiella
pneumoniae. However, increasing utilization has led to rising drug resistance and treatment …

ABSTRACT Introduction Carbonic anhydrases (CAs, EC 4.2. 1.1) play a pivotal role in the
regulation of carbon dioxide, bicarbonate, and hydrogen ions within bacterial cells, ensuring …

Acinetobacter baumannii is an extracellular opportunistic human pathogen that is becoming
increasingly problematic in hospitals. In the present study, we demonstrate that the A …

Background Healthcare‐associated antibiotic‐resistant (AR) infections increase patient
morbidity and mortality and might be impossible to successfully treat with any antibiotic …

Healthcare-associated infections (HAIs) represent a relevant problem for all healthcare
facilities, because they involve both the care aspect and the economic management of the …

Microorganisms have gained defense systems during the lengthy process of evolution over
millions of years. Such defense systems can protect them from being attacked by invading …

Bacterial infections are an imminent global healthcare threat evolving from rapidly
advancing bacterial defence mechanisms that antibiotics fail to overcome. Antibiotics have …

Whether multidrug resistance (MDR) is associated with mortality in patients with
Pseudomonas aeruginosa bloodstream infections (BSI) remains controversial. Here, we …

This review deeply addresses for the first time the diversity, regulation and mechanisms
leading to mutational overexpression of intrinsic β-lactamases from non-fermenting and …