Mechanistic roles of matrilin-2 and klotho in modulating the inflammatory activity of human aortic valve cells

E The, Q Yao, P Zhang, Y Zhai, L Ao, DA Fullerton… - Cells, 2020 - mdpi.com
Background: Calcific aortic valve disease (CAVD) is a chronic inflammatory disease. Soluble
extracellular matrix (ECM) proteins can act as damage-associated molecular patterns and …

Lack of Matrilin-2 Favors Liver Tumor Development via Erk1/2 and GSK-3β Pathways In Vivo

A Fullar, K Baghy, F Deak, B Peterfia, Y Zsak, P Tatrai… - PloS one, 2014 - journals.plos.org
Matrilin-2 (Matn2) is a multidomain adaptor protein which plays a role in the assembly of
extracellular matrix (ECM). It is produced by oval cells during stem cell-driven liver …

Extracellular matrix evolution: an overview

JC Adams - Evolution of extracellular matrix, 2013 - Springer
The extracellular matrix (ECM) is a central mediator of multicellularity in the metazoa. ECM
bridges between cells, provides mechanical support to tissues and is a source of signalling …

Adipocytes play an etiological role in the podocytopathy of high-fat diet-fed rats

JY Chen, DY Jian, CC Lien, YT Lin… - Journal of …, 2016 - joe.bioscientifica.com
It has recently been suggested that interleukin (IL)-11 plays a role in the pathogenesis of
glucocorticoid (GC)-induced osteoporosis. IL-11 belongs to the gp130 cytokine family, which …

Mantle Branch-Specific RNA Sequences of Moon Scallop Amusium pleuronectes to Identify Shell Color-Associated Genes

R Huang, Z Zheng, Q Wang, X Zhao, Y Deng, Y Jiao… - PLoS …, 2015 - journals.plos.org
Amusium pleuronectes (Linnaeus) that secretes red-and white-colored valves in two
branches of mantle tissues is an excellent model for shell color research. High-throughput …

[HTML][HTML] Doxorubicin-triggered self-assembly of native amphiphilic peptides into spherical nanoparticles

X Fan, F Zhao, X Wang, G Wu - Oncotarget, 2016 - ncbi.nlm.nih.gov
In this study, we designed and fabricated self-assembly nanospheres, which consisted of a
P45 peptide and doxorubicin (Dox). P45 is a hybrid peptide composed of an Arg-Gly-Asp …

Imbalanced cellular metabolism compromises cartilage homeostasis and joint function in a mouse model of mucolipidosis type III gamma

LM Westermann, L Fleischhauer… - Disease models & …, 2020 - journals.biologists.com
Mucolipidosis type III (MLIII) gamma is a rare inherited lysosomal storage disorder caused
by mutations in GNPTG encoding the γ-subunit of GlcNAc-1-phosphotransferase, the key …

Analysis of Polymorphisms in the MATN3 and DOT1L Genes and CTX-II Urinary Levels in Patients with Knee Osteoarthritis in a Northeast Mexican-Mestizo …

FJ García-Alvarado, HA Delgado-Aguirre… - Genetic Testing and …, 2020 - liebertpub.com
Aims: To investigate the possible roles of the single nucleotide polymorphisms (SNPs)
MATN3 (rs77245812) and DOT1L (rs12982744) with susceptibility to knee osteoarthritis …

A Cartilage Matrix Protein Regulates Collagen Synthesis in Mantle of Magallana gigas (Crassostrea gigas) under Ocean Acidification

T Zhu, C Liu, Z Liu, Y Gao, X Xin, L Wang, L Song - Fishes, 2023 - mdpi.com
The shell biosynthesis of oysters plays a critical role in protection against environmental
stress, in which cartilage matrix proteins (CMPs) determine the mineralogical and …

СОВРЕМЕННЫЙ ВЗГЛЯД НА СТРОЕНИЕ И ЭВОЛЮЦИЮ КОЛЛАГЕНОВ. II. КОЛЛАГЕНЫ, АССОЦИИРОВАННЫЕ С ФИБРИЛЛАМИ

ВП Иванова, АИ Кривченко - Журнал эволюционной биохимии и …, 2014 - elibrary.ru
Коллагены, ассоциированные с фибриллами (КАФ), образуют одно из подсемейств,
входящих в состав семейства коллагенов. Являясь минорными компонентами …