Idiopathic or primary osteoarthritis is a progressive musculoskeletal disease of diarthrodial
synovial joints, whereas secondary osteoarthritis generally arises from an antecedent …

Objective Cartilage oligomeric matrix protein (COMP) and matrilin 3 are extracellular matrix
proteins that are abundant in cartilage. As adaptor molecules, both proteins bridge and …

This study aimed at evaluating the effect of high glucose on the expression of extracellular
matrix (ECM) protein Matrilin-2 and the mechanism underlying this effect by using a mouse …

Mutations in matrilin-3 are associated with common skeletal diseases, such as hand
osteoarthritis (HOA), as well as rare chondrodysplasias, such as multiple epiphyseal …

Matrilin-2 is a widely distributed, oligomeric extracellular matrix protein that forms a
filamentous network by binding to a variety of different extracellular matrix proteins. We …

Endochondral ossification is the process that results in both the replacement of the
embryonic cartilaginous skeleton during organogenesis and the growth of long bones until …

目的探讨滨蒿内酯防治过量对乙酰氨基酚(APAP) 诱导的小鼠急性肝损伤的作用及其机制.
方法30 只C57BL/6 小鼠按体质量随机分对照组, 模型组, N-乙酰-L-半胱氨酸(NAC) …

Genetics is an area of study that connects genes with functions, variations with phenotypes,
and, of most interest to scientists and clinicians, mutations with diseases. According to the …

Abstract Background & Aims Matrilins are a family of four oligomeric adaptor proteins whose
functions in extracellular matrix assembly during pathophysiological events still need to be …

Live weight (LWT) in dairy cattle is associated with milk production efficiency, and also has a
high genetic correlation with stature. To identify genetic regions impacting stature and LWT …