Artificial extracellular matrices composed of collagen I and high-sulfated hyaluronan promote phenotypic and functional modulation of human pro-inflammatory M1 …

S Franz, F Allenstein, J Kajahn, I Forstreuter, V Hintze… - Acta biomaterialia, 2013 - Elsevier
The sequential phases of biomaterial integration and wound healing require different
macrophage functions mediated by distinct macrophage subsets. During the initial phase of …

Potential Role of Granulocyte–Monocyte Colony-Stimulating Factor in the Progression of Intracranial Aneurysms

N Chalouhi, T Theofanis, RM Starke, M Zanaty… - DNA and cell …, 2015 - liebertpub.com
Macrophages play a central role in the inflammatory response leading to aneurysm
formation, progression, and rupture. The purpose of this study was to determine whether …

Conformational requirements of suramin to target angiogenic growth factors

PA Raj, E Marcus, R Rein - Angiogenesis, 1998 - Springer
The conformational requirements of suramin for its binding to basic fibroblast growth factor
(bFGF) and platelet-derived growth factor (PDGF) were examined by molecular modeling …

Mapping the structural and dynamic determinants of pH-sensitive heparin binding to granulocyte macrophage Colony stimulating factor

JY Cui, F Zhang, L Nierzwicki, G Palermo… - Biochemistry, 2020 - ACS Publications
Granulocyte macrophage colony stimulating factor (GMCSF) is an immunomodulatory
cytokine that is harnessed as a therapeutic. GMCSF is known to interact with other clinically …

Combination anti-leukemic therapy by utilizing suramin and biologic response modifiers

MA Doukas - US Patent 6,121,320, 2000 - Google Patents
Krystyna Gnacinska et al.,“Block of the macrophage System and blood lipids”, 88004n, 1-
Pharmacodynamics, vol. 92, 1980, p. 35. Abstract Only. V. Dimov et al.,“Phagocytic and …

Suramin-induced neutropenia

NA Dawson, RM Lush, SM Steinberg… - European Journal of …, 1996 - Elsevier
This paper presents a retrospective review of 6 cases of severe neutropenia attributed to
suramin, the response to granulocyte-colony stimulating factor (G-CSF) and the possible …

Identification of an Adenine–Nucleotide–Binding Site on Interferon α2

MC Olcott, BE Haley - European journal of biochemistry, 1997 - Wiley Online Library
Using 32P‐labeled 2‐azidoadenosine 5′‐triphosphate (2N3ATP) and 8‐azidoadenosine
5′‐triphosphate (8N3ATP), we have identified a site on human interferon α2 (IFN‐α2) that …

[PDF][PDF] Relatórios de Estágio realizado na Farmácia Medeiros e no Hospital Garcia de Orta

DF Correia - 2018 - repositorio-aberto.up.pt
O estágio curricular apresenta-se como uma prova final de preparação para o futuro,
permitindo-nos aplicar os conhecimentos adquiridos ao longo do percurso académico e …