Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases

AB Kunnumakkara, D Bordoloi… - British journal of …, 2017 - Wiley Online Library
Curcumin, a yellow pigment in the Indian spice Turmeric (Curcuma longa), which is
chemically known as diferuloylmethane, was first isolated exactly two centuries ago in 1815 …

[HTML][HTML] Curcumin: An epigenetic regulator and its application in cancer

T Ming, Q Tao, S Tang, H Zhao, H Yang, M Liu… - Biomedicine & …, 2022 - Elsevier
Nowadays, one of the leading causes of death in humans is cancer, which is still on the rise
globally and is in great need of intense study on the pathogenic mechanism and effective …

Polyphenols and neuroprotection: Therapeutic implications for cognitive decline

G Caruso, SA Torrisi, MP Mogavero, W Currenti… - Pharmacology & …, 2022 - Elsevier
Dietary polyphenols have been the focus of major interest for their potential benefits on
human health. Several preclinical studies have been conducted to provide a rationale for …

[HTML][HTML] Recent developments in delivery, bioavailability, absorption and metabolism of curcumin: the golden pigment from golden spice

S Prasad, AK Tyagi… - Cancer research and …, 2014 - synapse.koreamed.org
Curcumin (diferuloylmethane) is a yellow pigment present in the spice turmeric (Curcuma
longa) that has been associated with antioxidant, anti-inflammatory, anticancer, antiviral …

The beneficial role of curcumin on inflammation, diabetes and neurodegenerative disease: A recent update

S Ghosh, S Banerjee, PC Sil - Food and Chemical Toxicology, 2015 - Elsevier
The concept of using phytochemicals has ushered in a new revolution in pharmaceuticals.
Naturally occurring polyphenols (like curcumin, morin, resveratrol, etc.) have gained …

The anti-inflammatory properties of phytochemicals and their effects on epigenetic mechanisms involved in TLR4/NF-κB-mediated inflammation

HA Saleh, MH Yousef, A Abdelnaser - Frontiers in immunology, 2021 - frontiersin.org
Innate immune response induces positive inflammatory transducers and regulators in order
to attack pathogens, while simultaneously negative signaling regulators are transcribed to …

Potential of curcumin in skin disorders

L Vollono, M Falconi, R Gaziano, F Iacovelli, E Dika… - Nutrients, 2019 - mdpi.com
Curcumin is a compound isolated from turmeric, a plant known for its medicinal use.
Recently, there is a growing interest in the medical community in identifying novel, low-cost …

Is curcumin bioavailability a problem in humans: Lessons from clinical trials

AB Kunnumakkara, C Harsha, K Banik… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Since ancient times, turmeric has been used in several folklore remedies
against various ailments. The principal component of turmeric is curcumin and its efficacy …

Curcumin—from molecule to biological function

T Esatbeyoglu, P Huebbe, IMA Ernst… - Angewandte Chemie …, 2012 - Wiley Online Library
Turmeric is traditionally used as a spice and coloring in foods. It is an important ingredient in
curry and gives curry powder its characteristic yellow color. As a consequence of its intense …

The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancer

M Heger, RF van Golen, M Broekgaarden… - Pharmacological …, 2014 - ASPET
This review addresses the oncopharmacological properties of curcumin at the molecular
level. First, the interactions between curcumin and its molecular targets are addressed on …