A rift that has opened up between basic research (bench) and clinical research and patients
(bed) who need their new treatments, diagnostics and prevention, and this rift is widening …

An individualized innovative disease management is of great importance for people with
multiple sclerosis (pwMS) to cope with the complexity of this chronic, multidimensional …

Abstract The Human Phenotype Ontology (HPO)—a standardized vocabulary of phenotypic
abnormalities associated with 7000+ diseases—is used by thousands of researchers …

The term “precision medicine” has become very popular over recent years, fuelled by
scientific as well as political perspectives. Despite its popularity, its exact meaning, and how …

Following in the footsteps of other large “population neuroscience” studies, the Adolescent
Brain Cognitive Development℠(ABCD) study is the largest in the US assessing brain …

Importance Surgeons make complex, high-stakes decisions under time constraints and
uncertainty, with significant effect on patient outcomes. This review describes the …

Simple Summary The genomics-based concept of precision medicine began to emerge
following the completion of the Human Genome Project. In contrast to evidence-based …

Deep phenotyping has been defined as the precise and comprehensive analysis of
phenotypic abnormalities in which the individual components of the phenotype are observed …

The translation of the growing increase of findings emerging from basic nutritional science
into meaningful and clinically relevant dietary advices represents nowadays one of the main …

Discovering the genetic basis of a Mendelian phenotype establishes a causal link between
genotype and phenotype, making possible carrier and population screening and direct …