Bioengineered skin organoids: from development to applications

ZX Hong, ST Zhu, H Li, JZ Luo, Y Yang, Y An… - Military Medical …, 2023 - Springer
Significant advancements have been made in recent years in the development of highly
sophisticated skin organoids. Serving as three-dimensional models that mimic human skin …

Small extracellular vesicles: Yields, functionalization and applications in diabetic wound management

X Liu, Q Wei, Z Sun, S Cui, X Wan, Z Chu… - Interdisciplinary …, 2023 - Wiley Online Library
Diabetic wounds have imposed a significant burden on both patients and society with
prolonged healing processes hindered by dysfunctional skin repair cells. Small extracellular …

Biomimetic gland models with engineered stratagems

X Lin, L Sun, M Lu, Y Zhao - Research, 2023 - spj.science.org
As extensively distributed tissues throughout the human body, glands play a critical role in
various physiological processes. Therefore, the construction of biomimetic gland models in …

Endogenous tagging using split mNeonGreen in human iPSCs for live imaging studies

MC Husser, NP Pham, C Law, FRB Araujo, VJJ Martin… - Elife, 2024 - elifesciences.org
Endogenous tags have become invaluable tools to visualize and study native proteins in live
cells. However, generating human cell lines carrying endogenous tags is difficult due to the …

Recreating Human Skin In Vitro: Should the Microbiota Be Taken into Account?

A Galvan, C Pellicciari, L Calderan - International Journal of Molecular …, 2024 - mdpi.com
Skin plays crucial roles in the human body: besides protecting the organism from external
threats, it acts as a thermal regulator, is responsible for the sense of touch, hosts microbial …

Etude des mécanismes moléculaires de l'épidermolyse bulleuse simple à partir de cellules souches humaines induites à la pluripotence

S Martineau - 2024 - theses.hal.science
L'Epidermolyse bulleuse simplex (EBS) est une maladie cutanée principalement causée par
des mutations dominantes dans les gènes codant les kératines 5 (KRT5) ou 14 (KRT14) …