Considering that cancer continues to be an important cause of death worldwide, several
conventional anticancer treatments are widely used. However, most of them display low …

Cancer, a highly heterogeneous disease at intra/inter patient levels, remains a serious
health problem contributing to significant morbidity and mortality worldwide. Despite great …

Different hybrids based on curcumin and resveratrol were previously synthesized and
characterized by spectroscopic techniques. The most active molecules (3a, 3e, 3i, and 3k) …

With an intention of identifying chalcone derivatives exhibiting anti-protozoal activity, a
cohort of relatively unexplored arylpyrrole-based chalcone derivatives were synthesized in …

Eight hybrids based on genistein and aspirin were designed, synthesized, and elucidated by
spectroscopic analysis. Chemopreventive potential of these compounds was evaluated …

In this paper, we have assessed the design, synthesis, characterization, anticancer
properties, toxicity, and in silico study of 8-piperazinyl caffeinyl-triazolylmethyl derivatives as …

Dihydroberberine (DHBER), the partially reduced form of the alkaloid berberine (BER), is
known to exhibit important biological activities. Despite this fact, there have been only few …

Protozoan parasites represent a significant risk for public health worldwide, afflicting
particularly people in more vulnerable categories and cause large morbidity and heavy …

Chalcones are chemical precursors of flavonoids and exhibit a variety of biological
properties, including anti-cancer, anti-inflammatory, and anti-malarial activities. According to …

The synthesis, antitrypanosomal, and cytotoxic activities of 17 furanchalcone derivatives are
described herein. The structure of the synthesized products was elucidated by a …