Non-small cell lung cancer: Emerging molecular targeted and immunotherapeutic agents

T Singh, MF Hassanabad, AF Hassanabad - Biochimica et Biophysica Acta …, 2021 - Elsevier
Non-small cell lung cancer (NSCLC) represents the most common and fatal type of primary
lung malignancies. NSCLC is often diagnosed at later stages and requires systemic …

Impacts of frailty on prognosis in lung cancer patients: a systematic review and meta-analysis

S Dai, M Yang, J Song, S Dai, J Wu - Frontiers in Medicine, 2021 - frontiersin.org
Background: Frailty is a common geriatric syndrome and is described as a limited ability to
compensate and recover from stressors. Lung cancer is largely diagnosed in old age, when …

[HTML][HTML] Prognostic factors of 112 elderly patients with advanced non-small cell lung cancer

F Ran, Q Liu - Pakistan Journal of Medical Sciences, 2022 - ncbi.nlm.nih.gov
Objectives: In this study we retrospectively analyzed the prognostic factors of patients with
advanced non-small cell lung cancer (NSCLC). Methods: Clinical data of 112 patients with …

Real-world data on the first-line immune checkpoint inhibitors or in combination with chemotherapy in older patients (aged≥ 75 years) with advanced non-small cell …

P Zhang, M Ma, J Nie, L Dai, W Hu, J Zhang, D Wu… - Heliyon, 2024 - cell.com
Purpose The purpose of this study is to investigate the efficacy and safety of immune
checkpoint inhibitors (ICIs) or plus with chemotherapy in older patients. Methods We …

[HTML][HTML] Lung Cancer: New Directions in Senior Patients Assessment

AI Pîslaru, SM Albișteanu, AC Ilie, R Ștefaniu, A Mârza… - Geriatrics, 2024 - mdpi.com
Age is but one significant prognostic factor in lung cancer, influencing survival, treatment
response, and outcomes. This narrative review synthesizes findings from searches of 11 …

[HTML][HTML] Comparison of clinical efficacy between chrono-chemotherapy and conventional chemotherapy in patients with non-small cell lung cancer

Z Shang, J Li - American Journal of Cancer Research, 2023 - ncbi.nlm.nih.gov
This work focused on the clinical efficacy of chrono-chemotherapy and conventional
chemotherapy on patients with non-small cell lung cancer (NSCLC), providing a theoretical …

Establishment of a prognostic nomogram for elderly patients with limited-stage small cell lung cancer receiving radiotherapy

L Zhang, Q Zhang, Q Wu, L Zhao, Y Gao, X Li… - Scientific Reports, 2024 - nature.com
The present study explored the risk factors associated with radiotherapy in seniors
diagnosed with limited-stage small cell lung cancer (LS-SCLC) to construct and validate a …

[PDF][PDF] Survival evaluation in patients over 70 years of age with advanced stage non-small cell lung cancer

A Ozturk, O Oruc, MH Igde, OB Topcuoglu, M Kavas… - Eurasian J Med …, 2023 - ejmi.org
Objectives: Non-small cell lung (NSCLC) cancer is usually seen in elderly patients. The
impact of over 70 age on the survival of patients with NSCLC has not been studied. This …

[HTML][HTML] Efficacy and safety of S-1 compared with Docetaxel in elderly patients with advanced NSCLC previously treated with Platinum-based chemotherapy: a …

JCH Yang, TSK Mok, S Lu, K Nakagawa… - JTO Clinical and …, 2021 - Elsevier
Introduction Despite recent advances in NSCLC treatment, specific data on the elderly
population remain limited. In this post hoc subgroup analysis of the East Asia S-1 Trial in …

Platinum-Based Chemotherapy in Older Patients with Non-Small Cell Lung Cancer: What to Expect in the Real World

G Pelizzari, F Cortiula, M Giavarra, M Bartoletti… - Drugs & Aging, 2020 - Springer
Background The role of platinum-based chemotherapy (PBC) for the treatment of older
patients with non-small cell lung cancer (NSCLC) is still a matter of debate, despite the …