The dimethyhydrazine (DMH) or azoxymethane (AOM) model is a well‐established, well‐
appreciated, and widely used model of experimental colon carcinogenesis. It has many …

Animal models of colorectal carcinogenesis represent invaluable research tool for
investigating colorectal cancer (CRC). Experimentally induced tumours in laboratory …

Colon cancer is one of the leading causes of cancer mortality, worldwide. Cancer stem cells
are attractive targets for therapeutic interventions since their abnormal growth may trigger …

Colon rectal cancer (CRC) is the second commonest malignancy in developed countries
and a significant cause of mortality. Tenofovir reportedly reduces the risk of hepatocellular …

Background Vernonia auriculifera Hiern (Asteraceae) is among Ethiopian herbal medicines
that are traditionally used to treat skin and gastrointestinal cancers. In this study, the …

The modifying effects of aqueous yacon extract (AYE) and Lactobacillus acidophilus CRL
1014 against colon carcinogenesis induced by 1, 2-dimethylhydrazine (DMH) in male Wistar …

Objective: Much research has been conducted to identify natural antioxidant and
antimutagenic compounds capable of preventing, reverting or treating conditions caused by …

Objective Cyclooxygenase-2 (COX-2) has been shown to have an important role in
carcinogenesis. Elevated COX-2 expression has been reported in several human tumours …

An in vivo trial was conducted on seventy five rats allocated to three groups, first group was
DMH control group, second group was Wheat bran-DMH group (WB-DMH) in which wheat …

Spices are defined as any aromatic condiment of plant origin used to alter the flavor and
aroma of foods. Besides flavor and aroma, many spices have antioxidant activity, mainly …