Chronic obstructive pulmonary disease (COPD) is the end result of a series of dynamic and
cumulative gene–environment interactions over a lifetime. The evolving understanding of …

This document reviews 1) the measurement properties of commonly used exercise tests in
patients with chronic respiratory diseases and 2) published studies on their utilty and/or …

Chronic obstructive pulmonary disease (COPD) is a preventable and treatable lung disease
characterized by airflow limitation that is not fully reversible. In a significant proportion of …

Activity-related dyspnoea is often the most distressing symptom experienced by patients with
chronic obstructive pulmonary disease (COPD) and can persist despite comprehensive …

Chronic obstructive lung disease (COPD) is responsible for substantial rates of mortality and
economic burden, and is one of the most important public-health concerns. As the disease …

Low inspiratory capacity (IC), chronic dyspnea, and reduced exercise capacity are
inextricably linked and are independent predictors of increased mortality in chronic …

Dyspnea, exercise intolerance, and activity restriction are already apparent in mild chronic
obstructive pulmonary disease (COPD). However, patients may not seek medical help until …

Rationale: Bronchodilator therapy represents a potentially valuable therapeutic option to
increase exercise tolerance and enhance lung function in mild to moderate chronic …

There is increasing focus on understanding the nature of chronic obstructive pulmonary
disease (COPD) during the earlier stages. Mild COPD (Global Initiative for Chronic …

Chronic obstructive pulmonary disease (COPD), characterized by chronic airways
inflammation and progressive airflow limitation, is a common, preventable and treatable …