[HTML][HTML] Current approaches of nanomedicines in the market and various stage of clinical translation

X Shan, X Gong, J Li, J Wen, Y Li, Z Zhang - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Compared with traditional drug therapy, nanomedicines exhibit intriguing biological features
to increase therapeutic efficiency, reduce toxicity and achieve targeting delivery. This review …

Stimuli-activable metal-bearing nanomaterials and precise on-demand antibacterial strategies

Y Zhong, XT Zheng, S Zhao, X Su, XJ Loh - ACS nano, 2022 - ACS Publications
Bacterial infections remain the leading cause of death worldwide today. The emergence of
antibiotic resistance has urged the development of alternative antibacterial technologies to …

Green Synthesis and Characterization of Silver Nanoparticles Using Flaxseed Extract and Evaluation of Their Antibacterial and Antioxidant Activities

AK Alzubaidi, WJ Al-Kaabi, AA Ali, S Albukhaty… - Applied Sciences, 2023 - mdpi.com
Bioactive plant chemicals are considered to be rich and useful for creating nanomaterials.
The current work investigated the biosynthesis of silver nanoparticles (AgNPs) using …

Electroactive materials: Innovative antibacterial platforms for biomedical applications

J Li, Y Feng, W Chen, S Zhang, J Ma, S Chen… - Progress in Materials …, 2023 - Elsevier
Bacterial infection and antimicrobial resistance have been a severe worldwide threat to
human health. Therefore, alternative antimicrobial strategies that avoid resistance …

Infection microenvironment-activated nanoparticles for NIR-II photoacoustic imaging-guided photothermal/chemodynamic synergistic anti-infective therapy

N Yang, H Guo, C Cao, X Wang, X Song, W Wang… - Biomaterials, 2021 - Elsevier
Subcutaneous abscesses caused by drug-resistant bacteria pose huge challenges to
human health. The design of infection microenvironment-activated biomaterials has an …

Engineered live bacteria suppress Pseudomonas aeruginosa infection in mouse lung and dissolve endotracheal-tube biofilms

R Mazzolini, I Rodríguez-Arce, L Fernández-Barat… - Nature …, 2023 - nature.com
Engineered live bacteria could provide a new modality for treating lung infections, a major
cause of mortality worldwide. In the present study, we engineered a genome-reduced …

Bioinspired drug delivery strategies for repurposing conventional antibiotics against intracellular infections

S Subramaniam, P Joyce, N Thomas… - Advanced Drug Delivery …, 2021 - Elsevier
Bacteria have developed a wealth of strategies to avoid and resist the action of antibiotics,
one of which involves pathogens invading and forming reservoirs within host cells. Due to …

Nanoparticle-mediated stimulus-responsive antibacterial therapy

N Bag, S Bardhan, S Roy, J Roy, D Mondal… - Biomaterials …, 2023 - pubs.rsc.org
The limitations associated with conventional antibacterial therapies and the subsequent
amplification of multidrug-resistant (MDR) microorganisms have increased, necessitating the …

Stimuli-responsive nanocarriers for bacterial biofilm treatment

M Ding, W Zhao, LJ Song, SF Luan - Rare Metals, 2022 - Springer
Bacterial biofilm infections have been threatening the human's life and health globally for a
long time because they typically cause chronic and persistent infections. Traditional …

A NIR-II emissive polymer AIEgen for imaging-guided photothermal elimination of bacterial infection

Y Huang, D Li, D Wang, X Chen, L Ferreira… - Biomaterials, 2022 - Elsevier
The development of antibiotics resistance has made multidrug-resistant (MDR) bacterial
infection one of the most serious global health issues. Photothermal therapy (PTT) is an …